Questionnaire-Based Express Diagnostics of the Human Aging Rate

— An express method for the diagnosis of the rate of human aging has been developed based on a questionnaire that includes 15 indices of aging. The panel of biomarkers developed for the determination of biological age was validated with the Bayesian method and neural network analysis. The average er...

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Bibliographic Details
Published in:Advances in gerontology 2021-07, Vol.11 (3), p.283-289
Main Authors: Pisaruk, A. V., Koshel, N. M., Mehova, L. V., Pisaruk, L. V., Vaiserman, A. M.
Format: Article
Language:English
Subjects:
Age groups
Aging
Geriatrics/Gerontology
Gerontology
Medicine
Medicine & Public Health
Methods
Neural networks
Physiology
Questionnaires
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Summary:— An express method for the diagnosis of the rate of human aging has been developed based on a questionnaire that includes 15 indices of aging. The panel of biomarkers developed for the determination of biological age was validated with the Bayesian method and neural network analysis. The average error in the determination of the biological age estimated with the Bayesian method was 14.5 years. Training of the neural network on a data array of 412 people provided significantly better results: the error was 7.5 years. The proposed method is simple, easy, rapid, and can readily be applied in outpatient and inpatient conditions. It does not require instrumental or laboratory examinations. This technique can be used to prescreen patients at risk of accelerated aging for further in-depth research.
ISSN:2079-0570
2079-0589
DOI:10.1134/S2079057021030097