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Sensitive SERS detection of Tobramycin using electrochemically synthesized silver nanoparticles

Sensitive surface-enhanced Raman spectroscopy (SERS) substrates designed for drug sensing are in great interest due to the growing demand in environmental monitoring, disease therapies and chemical analysis. Here, spherical silver nanoparticles (Ag-NPs; ~8 nm) are synthesized via a simple electroche...

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Published in:Bulletin of materials science 2022-10, Vol.45 (4), p.211, Article 211
Main Authors: Siddiqui, Hafsa, Singh, Netrapal, Khan, Rasheda, Sharma, Ritu, Goswami, Manoj, Kumar, Satendra, Kumar, Suneel, Sathish, N, Patel, Shiv Singh, Khan, Mohd. Akram, Kumar, Surender
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cited_by cdi_FETCH-LOGICAL-c319t-426b48c84d56daad8adc636cd0a395019ae80856cf1c1559fe76e5fcc5453d603
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container_title Bulletin of materials science
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creator Siddiqui, Hafsa
Singh, Netrapal
Khan, Rasheda
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Goswami, Manoj
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Kumar, Suneel
Sathish, N
Patel, Shiv Singh
Khan, Mohd. Akram
Kumar, Surender
description Sensitive surface-enhanced Raman spectroscopy (SERS) substrates designed for drug sensing are in great interest due to the growing demand in environmental monitoring, disease therapies and chemical analysis. Here, spherical silver nanoparticles (Ag-NPs; ~8 nm) are synthesized via a simple electrochemical route and examined as SERS substrates for Tobramycin (TOBi) detection. The morphology and structure characterizations confirm the successful fabrication of Ag-NP. TOBi in diluted solution has a detection limit of 10 −6 M, and the linear relationship between SERS intensity and TOBi amount is between 10 −6 and 10 −5 M. A strong SER signal with an enhancement factor of ~7.5 × 10 4 is observed. TOBi drug is for the first time investigated through Ag-based SERS detection. Graphical abstract
doi_str_mv 10.1007/s12034-022-02790-6
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source Indian Academy of Sciences; Springer Nature:Jisc Collections:Springer Nature Read and Publish 2023-2025: Springer Reading List
subjects Antibiotics
Aqueous solutions
Chemical analysis
Chemistry and Materials Science
Electrodes
Electrolytes
Engineering
Environmental monitoring
Indium tin oxides
Materials Science
Nanomaterials
Nanoparticles
Particle size
Raman spectroscopy
Silver
Substrates
Voltammetry
title Sensitive SERS detection of Tobramycin using electrochemically synthesized silver nanoparticles
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