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Sensitive SERS detection of Tobramycin using electrochemically synthesized silver nanoparticles
Sensitive surface-enhanced Raman spectroscopy (SERS) substrates designed for drug sensing are in great interest due to the growing demand in environmental monitoring, disease therapies and chemical analysis. Here, spherical silver nanoparticles (Ag-NPs; ~8 nm) are synthesized via a simple electroche...
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Published in: | Bulletin of materials science 2022-10, Vol.45 (4), p.211, Article 211 |
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container_issue | 4 |
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container_title | Bulletin of materials science |
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creator | Siddiqui, Hafsa Singh, Netrapal Khan, Rasheda Sharma, Ritu Goswami, Manoj Kumar, Satendra Kumar, Suneel Sathish, N Patel, Shiv Singh Khan, Mohd. Akram Kumar, Surender |
description | Sensitive surface-enhanced Raman spectroscopy (SERS) substrates designed for drug sensing are in great interest due to the growing demand in environmental monitoring, disease therapies and chemical analysis. Here, spherical silver nanoparticles (Ag-NPs; ~8 nm) are synthesized via a simple electrochemical route and examined as SERS substrates for Tobramycin (TOBi) detection. The morphology and structure characterizations confirm the successful fabrication of Ag-NP. TOBi in diluted solution has a detection limit of 10
−6
M, and the linear relationship between SERS intensity and TOBi amount is between 10
−6
and 10
−5
M. A strong SER signal with an enhancement factor of ~7.5 × 10
4
is observed. TOBi drug is for the first time investigated through Ag-based SERS detection.
Graphical abstract |
doi_str_mv | 10.1007/s12034-022-02790-6 |
format | article |
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−6
M, and the linear relationship between SERS intensity and TOBi amount is between 10
−6
and 10
−5
M. A strong SER signal with an enhancement factor of ~7.5 × 10
4
is observed. TOBi drug is for the first time investigated through Ag-based SERS detection.
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−6
M, and the linear relationship between SERS intensity and TOBi amount is between 10
−6
and 10
−5
M. A strong SER signal with an enhancement factor of ~7.5 × 10
4
is observed. TOBi drug is for the first time investigated through Ag-based SERS detection.
Graphical abstract</description><subject>Antibiotics</subject><subject>Aqueous solutions</subject><subject>Chemical analysis</subject><subject>Chemistry and Materials Science</subject><subject>Electrodes</subject><subject>Electrolytes</subject><subject>Engineering</subject><subject>Environmental monitoring</subject><subject>Indium tin oxides</subject><subject>Materials Science</subject><subject>Nanomaterials</subject><subject>Nanoparticles</subject><subject>Particle size</subject><subject>Raman spectroscopy</subject><subject>Silver</subject><subject>Substrates</subject><subject>Voltammetry</subject><issn>0973-7669</issn><issn>0250-4707</issn><issn>0973-7669</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2022</creationdate><recordtype>article</recordtype><recordid>eNp9kE9LAzEQxYMoWKtfwFPA82qy2WQ3Ryn1DxQEW88hTWbblG1Sk22hfnqjK-jJwzAD896b4YfQNSW3lJD6LtGSsKogZZmrlqQQJ2hEZM2KWgh5-mc-RxcpbQihsqroCKk5-OR6dwA8n77OsYUeTO-Cx6HFi7CMens0zuN9cn6FocvLGMwats7orjvidPT9GpL7AIuT6w4Qsdc-7HTsnekgXaKzVncJrn76GL09TBeTp2L28vg8uZ8VhlHZF1UpllVjmspyYbW2jbZGMGEs0Uzy_KyGhjRcmJYayrlsoRbAW2N4xZkVhI3RzZC7i-F9D6lXm7CPPp9UpSxzACOyyqpyUJkYUorQql10Wx2PihL1BVINIFUGqb5BKpFNbDClLPYriL_R_7g-Aaw6d_M</recordid><startdate>20221026</startdate><enddate>20221026</enddate><creator>Siddiqui, Hafsa</creator><creator>Singh, Netrapal</creator><creator>Khan, Rasheda</creator><creator>Sharma, Ritu</creator><creator>Goswami, Manoj</creator><creator>Kumar, Satendra</creator><creator>Kumar, Suneel</creator><creator>Sathish, N</creator><creator>Patel, Shiv Singh</creator><creator>Khan, Mohd. 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Akram</au><au>Kumar, Surender</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Sensitive SERS detection of Tobramycin using electrochemically synthesized silver nanoparticles</atitle><jtitle>Bulletin of materials science</jtitle><stitle>Bull Mater Sci</stitle><date>2022-10-26</date><risdate>2022</risdate><volume>45</volume><issue>4</issue><spage>211</spage><pages>211-</pages><artnum>211</artnum><issn>0973-7669</issn><issn>0250-4707</issn><eissn>0973-7669</eissn><abstract>Sensitive surface-enhanced Raman spectroscopy (SERS) substrates designed for drug sensing are in great interest due to the growing demand in environmental monitoring, disease therapies and chemical analysis. Here, spherical silver nanoparticles (Ag-NPs; ~8 nm) are synthesized via a simple electrochemical route and examined as SERS substrates for Tobramycin (TOBi) detection. The morphology and structure characterizations confirm the successful fabrication of Ag-NP. TOBi in diluted solution has a detection limit of 10
−6
M, and the linear relationship between SERS intensity and TOBi amount is between 10
−6
and 10
−5
M. A strong SER signal with an enhancement factor of ~7.5 × 10
4
is observed. TOBi drug is for the first time investigated through Ag-based SERS detection.
Graphical abstract</abstract><cop>Bangalore</cop><pub>Indian Academy of Sciences</pub><doi>10.1007/s12034-022-02790-6</doi><orcidid>https://orcid.org/0000-0003-3193-3746</orcidid></addata></record> |
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source | Indian Academy of Sciences; Springer Nature:Jisc Collections:Springer Nature Read and Publish 2023-2025: Springer Reading List |
subjects | Antibiotics Aqueous solutions Chemical analysis Chemistry and Materials Science Electrodes Electrolytes Engineering Environmental monitoring Indium tin oxides Materials Science Nanomaterials Nanoparticles Particle size Raman spectroscopy Silver Substrates Voltammetry |
title | Sensitive SERS detection of Tobramycin using electrochemically synthesized silver nanoparticles |
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