Possible Approaches to Increase the Longevity of Experimental Animals

A statistically significant difference in the cumulative survival of Wistar rats born in different seasons has been shown: animals born in late November–early December had an average lifespan 24.8% longer, a minimum lifespan 14.3% longer, and a maximum lifespan 20.7% longer in comparison with animal...

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Bibliographic Details
Published in:Advances in gerontology 2018-10, Vol.8 (4), p.271-276
Main Authors: Kulikov, A. V., Arkhipova, L. V., Kulikova, P. A., Glazkov, A. A., Kulikov, D. A.
Format: Article
Language:English
Subjects:
Age
Aging
Cornea
Geriatrics/Gerontology
Laboratory animals
Medicine
Medicine & Public Health
Surgery
Thymus gland
Transplants & implants
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Summary:A statistically significant difference in the cumulative survival of Wistar rats born in different seasons has been shown: animals born in late November–early December had an average lifespan 24.8% longer, a minimum lifespan 14.3% longer, and a maximum lifespan 20.7% longer in comparison with animals born in April. Transplantation of thymus tissue into the immune privileged anterior chamber of the eye in animals born both in November and April has shown a geroprotective effect.
ISSN:2079-0570
2079-0589
DOI:10.1134/S2079057018040100