Comparative analysis of the skin surface lipids between acne patients and controls using UFLC method

Acne is a chronic inflammatory disease of pilosebaceous units. This study aims to analyze the composition of skin surface lipids in patients with acne compared to controls to correlate the severity of acne. The severity of acne was graded according to the standard grading system in clinical terms. S...

Full description

Saved in:
Bibliographic Details
Published in:Accreditation and quality assurance 2024-02, Vol.29 (1), p.37-43
Main Authors: Walia, M. S., Vinutha, R., Shastry, V., Betkerur, J., Gurupadayya, B. M., Konala, H.
Format: Article
Language:English
Subjects:
Acne
Age groups
Analytical Chemistry
Biochemistry
Calibration
Chemistry
Chemistry and Materials Science
Chromatography
Commercial Law
Drug therapy
Ecotoxicology
Fatty acids
Females
Food Science
Hexanes
Lipids
Males
Marketing
Oleic acid
Pathogenesis
Pharmacology
Rubbing
Stearic acid
Ultraviolet detectors
Citations: Items that this one cites
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Acne is a chronic inflammatory disease of pilosebaceous units. This study aims to analyze the composition of skin surface lipids in patients with acne compared to controls to correlate the severity of acne. The severity of acne was graded according to the standard grading system in clinical terms. Skin surface lipid samples were collected by rubbing the skin over the face with a swab soaked in hexane for a minute. The analysis was performed by UFLC with a UV detector. Subjects with acne were found to have a significantly higher quantity of squalene ( p  
ISSN:0949-1775
1432-0517
DOI:10.1007/s00769-023-01568-5