An overview on: Anti psoriasis phytocomponents used in novel drug delivery systems

Psoriasis is proliferative autoimmune inflammatory skin disease which is mainly affecting 2 % of world population. The initial sign and symptoms is mainly characterized by itching, redness and silver scaly plaques over the skin. The pathogenesis of disease includes activation of T cells which may ca...

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Bibliographic Details
Main Authors: Kumar, Arun, Singh, Saurabh, Kumar, Bimlesh, Baghel, Dileep Singh, Sati, Bhawana, Chandra, Prakash
Format: Conference Proceeding
Language:English
Subjects:
Constituents
Drug delivery systems
Herbal medicine
Itching
Lipids
Lymphocytes
Pathogenesis
Psoriasis
Signs and symptoms
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Summary:Psoriasis is proliferative autoimmune inflammatory skin disease which is mainly affecting 2 % of world population. The initial sign and symptoms is mainly characterized by itching, redness and silver scaly plaques over the skin. The pathogenesis of disease includes activation of T cells which may cause release of cytokines leads to inflammation over skin. Various subtypes of psoriasis is reported i.e Plaque Psoriasis, Flexural Psoriasis, Pustular psoriasis, Generalized Pustular Psoriasis, Palmo plantar psoriasis, Guttate psoriasis, Psoriatic nail disease diagnosed by skin biopsy. Many herbal remedies alone or in with combination is being used for the treatment of various disease. Herbal chief constituents incorporated in novel drug delivery system plays an important role for the treatment of psoriasis. The aim of this review is to understand the importance of herbal active constituents which are used in the treatment of psoriasis by inhibiting cell proliferation and lipid peroxidation over skin. The review also discussed the potential approach of novel drug delivery over conventional drug delivery for treatment of psoratic lesions. In vitro studies also demonstrate the therapeutic potential of herbal phytoactive for the treatment of psoriasis. Plants selected in this review article is having great therapeutic potential in terms of treating psoriasis.
ISSN:0094-243X
1551-7616
DOI:10.1063/5.0192537