3D printing biomimetic materials and structures for biomedical applications

Over millions of years of evolution, nature has created organisms with overwhelming performances due to their unique materials and structures, providing us with valuable inspirations for the development of next-generation biomedical devices. As a promising new technology, 3D printing enables the fab...

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Bibliographic Details
Published in:Bio-design and manufacturing 2021-06, Vol.4 (2), p.405-428
Main Authors: Zhu, Yizhen, Joralmon, Dylan, Shan, Weitong, Chen, Yiyu, Rong, Jiahui, Zhao, Hanyu, Xiao, Siqi, Li, Xiangjia
Format: Article
Language:English
Subjects:
3-D printers
Artificial organs
Biomaterials
Biomedical Engineering and Bioengineering
Biomedical materials
Cell culture
Civil engineering
Design
Engineering
Extracellular matrix
Hydrogels
Lab-on-a-chip
Magnetic fields
Manufacturing
Mechanical Engineering
Mechanical properties
Medical device industry
Medical equipment
Medical research
Microvasculature
Nanomaterials
Polylactic acid
Polymers
Printing
Rapid prototyping
Review
Tissue engineering
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Summary:Over millions of years of evolution, nature has created organisms with overwhelming performances due to their unique materials and structures, providing us with valuable inspirations for the development of next-generation biomedical devices. As a promising new technology, 3D printing enables the fabrication of multiscale, multi-material, and multi-functional three-dimensional (3D) biomimetic materials and structures with high precision and great flexibility. The manufacturing challenges of biomedical devices with advanced biomimetic materials and structures for various applications were overcome with the flourishing development of 3D printing technologies. In this paper, the state-of-the-art additive manufacturing of biomimetic materials and structures in the field of biomedical engineering were overviewed. Various kinds of biomedical applications, including implants, lab-on-chip, medicine, microvascular network, and artificial organs and tissues, were respectively discussed. The technical challenges and limitations of biomimetic additive manufacturing in biomedical applications were further investigated, and the potential solutions and intriguing future technological developments of biomimetic 3D printing of biomedical devices were highlighted.
ISSN:2096-5524
2522-8552
DOI:10.1007/s42242-020-00117-0