Pharmacist-Directed Self-Management of Blood Pressure Versus Conventional Management in Patients with Hypertension: A Randomized Control Trial

Introduction Data has shown that pharmacist-directed health services play a key role in the treatment of hypertension. Aim We aimed to perform this study to compare two methods of the pharmacist-directed home blood pressure monitoring (HBPM) and the usual care. Methods A total of 126 patients with u...

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Bibliographic Details
Published in:High blood pressure & cardiovascular prevention 2021-05, Vol.28 (3), p.283-290
Main Authors: Khiali, Sajad, Khezerlo-aghdam, Naser, Namdar, Hossein, Entezari-Maleki, Taher
Format: Article
Language:English
Subjects:
Anticoagulants
Blood pressure
Cardiology
Chronic illnesses
Clinical outcomes
Consent
Diabetes
Drug stores
Heart
Hypertension
Intervention
Medicine
Medicine & Public Health
Original Article
Pharmacotherapy
Supervision
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Summary:Introduction Data has shown that pharmacist-directed health services play a key role in the treatment of hypertension. Aim We aimed to perform this study to compare two methods of the pharmacist-directed home blood pressure monitoring (HBPM) and the usual care. Methods A total of 126 patients with uncontrolled blood pressure (BP) were randomized 1:1 into the pharmacist-directed HBPM and the usual care groups. In the intervention group, the patients were trained to measure their BPs and adjust their medications based on the designed protocol under the supervision of a clinical pharmacist. The primary endpoint of the study was the comparison of the BPs at baseline and months 1, 3, and 6. Results One month after the allocation, the baseline systolic BP (SBP) (150.5 ± 13.1 vs. 149.7 ± 11.2 mm Hg; P = 0.71) and diastolic BP (DBP) (97.2 ± 9.8 vs. 93.6 ± 14.5; P = 0.11) significantly dropped to the control range equally in 85.2% of the patients in two groups (SBP: 128.8 ± 6.4 vs. 125.6 ± 7.1 mm Hg; P = 0.01 and DBP: 89.1 ± 6.2 vs. 81.5 ± 6.0 mm Hg; P = 0.01). This pattern continued during the study period (month 6; SBP: 115.6 ± 10.1vs. 116.1 ± 9.6 mm Hg; P = 0.78; DBP: 79.0 ± 5.0 vs. 77.2 ± 5.8 mm Hg; P = 0.08). Conclusions In this study, we did not observe any significant difference between the pharmacist-directed HBPM and usual care methods in decreasing BP.
ISSN:1120-9879
1179-1985
DOI:10.1007/s40292-021-00445-x