Electrospun Nanofibrous Materials for Wound Healing

Wound dressing materials which are capable of meeting the demands of accelerating wound closure and promoting wound healing process have being highly desired. Electrospun nanofibrous materials show great application potentials for wound healing owing to relatively large surface area, better mimicry...

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Bibliographic Details
Published in:Advanced fiber materials (Online) 2020-08, Vol.2 (4), p.212-227
Main Authors: Dong, Yuping, Zheng, Yuqi, Zhang, Keyan, Yao, Yueming, Wang, Lihuan, Li, Xiaoran, Yu, Jianyong, Ding, Bin
Format: Article
Language:English
Subjects:
Acids
Adsorption
Biological activity
Cellulose
Chemistry and Materials Science
Drug delivery systems
Growth factors
Hydrogels
Inflammation
Materials Engineering
Materials Science
Mimicry
Nanoscale Science and Technology
Permeability
Polymer Sciences
Polymers
Renewable and Green Energy
Review
Skin
Stem cells
Textile Engineering
Wound healing
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Summary:Wound dressing materials which are capable of meeting the demands of accelerating wound closure and promoting wound healing process have being highly desired. Electrospun nanofibrous materials show great application potentials for wound healing owing to relatively large surface area, better mimicry of native extracellular matrix, adjustable waterproofness and breathability, and programmable drug delivery process. In this review article, we begin with a discussion of wound healing process and current commercial wound dressing materials. Then, we emphasize on electrospun nanofibrous materials for wound dressing, covering the efforts for controlling fiber alignment and morphology, constructing 3D scaffolds, developing waterproof-breathable membrane, governing drug delivery performance, and regulating stem cell behavior. Finally, we finish with challenges and future prospects of electrospun nanofibrous materials for wound dressings. Graphic Abstract
ISSN:2524-7921
2524-793X
DOI:10.1007/s42765-020-00034-y