Concomitant Lymphocytic Colitis With Recurrent Clostridium difficile Infection

Microscopic colitis is a clinicopathological diagnosis that is characterized by chronic microscopic inflammation of the colon and presents with chronic watery diarrhea. There are following two subtypes of microscopic colitis: lymphocytic colitis and collagenous colitis. This is a case of a 70-year-o...

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Bibliographic Details
Published in:Curēus (Palo Alto, CA) CA), 2024-01, Vol.16 (1), p.e51606
Main Authors: Suleiman, Noor M, Baiyasi, Maya, Al-Saghir, Tala, Daines, Bryan, Patel, Falgun
Format: Article
Language:English
Subjects:
Abdomen
Antibiotics
Biopsy
Blood
Case reports
Colon
Colonoscopy
Diarrhea
Females
Gastroenterology
Infections
Infectious diseases
Inflammatory bowel disease
Medical imaging
Nursing homes
Patients
Primary care
Remission (Medicine)
Risk factors
Social history
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Summary:Microscopic colitis is a clinicopathological diagnosis that is characterized by chronic microscopic inflammation of the colon and presents with chronic watery diarrhea. There are following two subtypes of microscopic colitis: lymphocytic colitis and collagenous colitis. This is a case of a 70-year-old female with a history of infections who presented with persistent watery diarrhea and was diagnosed with lymphocytic colitis in the setting of a concomitant infection. Given her clinical presentation, the patient was initiated on empiric treatment for infection and showed a lack of clinical improvement with persistent watery diarrhea and elevated white blood cell count. The patient's symptoms resolved upon the confirmatory diagnosis and treatment of lymphocytic colitis. This study illustrates the importance of assessing for, diagnosing, and treating lymphocytic colitis in patients with chronic non-resolving watery diarrhea, especially in the setting of concomitant or recurrent infections. Additionally, it emphasizes the need for further characterization of the relationship between infection and microscopic colitis.
ISSN:2168-8184
2168-8184
DOI:10.7759/cureus.51606