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Development of a 3D subcutaneous construct containing insulin-producing beta cells using bioprinting

Type 1 diabetes is caused by insulin deficiency due to the loss of beta cells in the islets of Langerhans. In severe cases, islet transplantation into the portal vein is performed. However, due to the loss of transplanted islets and the failure of islet function, the 5-year insulin independence rate...

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Bibliographic Details
Published in:Bio-design and manufacturing 2022-04, Vol.5 (2), p.265-276
Main Authors: Ahn, Chi B., Lee, Ji-Hyun, Kim, Joo H., Kim, Tae H., Jun, Hee-Sook, Son, Kuk H., Lee, Jin W.
Format: Article
Language:English
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Summary:Type 1 diabetes is caused by insulin deficiency due to the loss of beta cells in the islets of Langerhans. In severe cases, islet transplantation into the portal vein is performed. However, due to the loss of transplanted islets and the failure of islet function, the 5-year insulin independence rate of these patients is 
ISSN:2096-5524
2522-8552
DOI:10.1007/s42242-021-00178-9