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Development of a 3D subcutaneous construct containing insulin-producing beta cells using bioprinting
Type 1 diabetes is caused by insulin deficiency due to the loss of beta cells in the islets of Langerhans. In severe cases, islet transplantation into the portal vein is performed. However, due to the loss of transplanted islets and the failure of islet function, the 5-year insulin independence rate...
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Published in: | Bio-design and manufacturing 2022-04, Vol.5 (2), p.265-276 |
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Main Authors: | , , , , , , |
Format: | Article |
Language: | English |
Subjects: | |
Citations: | Items that this one cites Items that cite this one |
Online Access: | Get full text |
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Summary: | Type 1 diabetes is caused by insulin deficiency due to the loss of beta cells in the islets of Langerhans. In severe cases, islet transplantation into the portal vein is performed. However, due to the loss of transplanted islets and the failure of islet function, the 5-year insulin independence rate of these patients is |
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ISSN: | 2096-5524 2522-8552 |
DOI: | 10.1007/s42242-021-00178-9 |