Characterization and biological applications of CaCO3@Co0.5Zn0.5Fe2O4 nanoparticles

CaCO 3 coating was applied to the surface of Co 0.5 Zn 0.5 Fe 2 O 4 (CZF) nanoparticles by chemical co-precipitation method. CaCO 3 -coated CZF(CC@CZF) and bare CZF nanoparticles have been characterized by spectroscopy and microscopy techniques. XRD patterns indicate the pure cubic spinel structure...

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Bibliographic Details
Published in:Applied physics. A, Materials science & processing Materials science & processing, 2024-04, Vol.130 (4), Article 215
Main Authors: Nimafar, Mona, El-Nabulsi, Rami Ahmad, Anukool, Waranont, Haris, Somayeh Asadi, Isfahani, Behzad Khatamsaz, Javanifar, Roshan, Dabagh, Shadab
Format: Article
Language:English
Subjects:
Calcium carbonate
Characterization and Evaluation of Materials
Condensed Matter Physics
Machines
Magnetic properties
Magnetic saturation
Manufacturing
Microscopy
Nanoparticles
Nanotechnology
Optical and Electronic Materials
Physics
Physics and Astronomy
Processes
Surfaces and Interfaces
Thin Films
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Summary:CaCO 3 coating was applied to the surface of Co 0.5 Zn 0.5 Fe 2 O 4 (CZF) nanoparticles by chemical co-precipitation method. CaCO 3 -coated CZF(CC@CZF) and bare CZF nanoparticles have been characterized by spectroscopy and microscopy techniques. XRD patterns indicate the pure cubic spinel structure of CZF nanoparticles and the growth of CaCO 3 layer on the nanoparticle’s surface. The spherical shape and the size distribution of the nanoparticles were assessed to be ~ 30 nm before coating and ~ 60 nm after surface functionalization and confirmed by the FESEM microscopy technique. The magnetic characteristics of samples were investigated using the vibrating sample magnetometer technique, which revealed a drop in saturation magnetization from 45 to 32 emu/g. So, coated nanoparticles performed effectively as drug transporters under both normal and magnetic field circumstances. Hydrodynamic diameters of CZF nanoparticles are ~ 726 nm and decrease to ~ 370 nm due to the surface functionalization and cause reducing particle aggregation. An MTT test was used to assess the dose-dependent cellular cytotoxicity and viability of normal human skin cells (HSF 1184), which revealed that CC@CZF nanoparticles are less harmful than bare nanoparticles.
ISSN:0947-8396
1432-0630
DOI:10.1007/s00339-024-07367-0