Evaluation of p53 in women diagnosis with breast cancer

• Main Authors: Jaber, Haider Yahya, Mohmmed Ali, Angham Jasim
• Format: Conference Proceeding
• Language: English
• Subjects: Age; Breast cancer; Diagnosis; Health services; Hormones; Women
• ISSN: 0094-243X; 1551-7616
• DOI: 10.1063/5.0200443

Breast cancer considers type of cancer that arises from the tissues of the a breast. Globally, breast cancer is estimated for 22.9% of all cancers in women. Usually, the first noticeable sign of breast cancer is a lump that looks different from the other breast tissues. The are main risk factors for breast cancer are female gender and older age. Smoking, genetics, lack of childbearing or breastfeeding, exposure to radio pollution and, elevated levels of certain hormones, dietary patterns are considered the other potential risk factors (2). Objectives: This study aims to identify the role of autoantibody P53 associated with women’s breast cancer. Methods: In order to gather medical data from (130) participants at the Imam Al-Sadiq General Teaching Hospital in Iraq-Babylon, the oncologist divided the subjects into two groups based on predetermined criteria: the a control group and the patient,s (case group). There demographic study covered age, education, marital status, and place of residence. According to laboratory findings, P53 levels were determined using the ELISA technique. Results: The results are revealed crucial variations in human protein (P53) association among breast cancer samples (case groups) and control groups. P53 level with the women breast cancer group. Acording age mean Std (48.26±8.55) case groups, (48.60±11.11) control groups. Acording total treatment of p53 for study groups means±Std (218.974±216.423) case groups, (182.988±19.960) control groups. p53 mean comparison between treatment groups for cases mean±Std (180.139±18.368) Acording before chemo, (238.989±274.923) Acording chemotherapy, (197.173±14.399) Acording hormonal, (218.975±216.424) Total. Conclusion: They might be viewed as reliable indicators for providing information concerning women’s breast cancer diagnosis:.