84 Circulating Vitamin D Levels and Frailty in the British Regional Heart Study: Cross Sectional and Prospective Associations

Abstract Introduction Whether Vitamin D deficiency is linked to development of frailty, independent of other health conditions, is inconclusive. In the British Regional Heart Study we aimed to examine (1) cross sectional (CS) and prospective (PS) associations between Vitamin D levels and frailty; an...

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Bibliographic Details
Published in:Age and ageing 2020-02, Vol.49 (Supplement_1), p.i27-i27
Main Authors: Ahmed, A, Ramsay, S E, Papacosta, O, Lennon, L, Whincup, P H, Wannamethee, S G
Format: Article
Language:English
Subjects:
Adjustment
Body mass index
C-reactive protein
Calcium
Chronic obstructive pulmonary disease
Clinical outcomes
Diabetes
Diabetes mellitus
Dietary supplements
Frail
Frailty
Habits
Health status
Interleukin 6
Lung diseases
Men
Mental health
Obstructive lung disease
Risk factors
Smoking
Social classes
Vitamin D
Vitamin deficiency
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Summary:Abstract Introduction Whether Vitamin D deficiency is linked to development of frailty, independent of other health conditions, is inconclusive. In the British Regional Heart Study we aimed to examine (1) cross sectional (CS) and prospective (PS) associations between Vitamin D levels and frailty; and (2) if these are mediated by conditions linked to low Vitamin D (diabetes, chronic obstructive pulmonary disease and inflammatory markers C-reactive protein & Interleukin-6). Methods Baseline (2010-2012) Vitamin D in men (71-92y) was categorised as deficiency (
ISSN:0002-0729
1468-2834
DOI:10.1093/ageing/afz192.02