Cover Feature: A Nanoplatform Based on Pillararene Nanovalves for Combined Drug Delivery and Enhanced Antitumor Activity

Pillar[5]arene acts like an intelligent robot to efficiently regulate drug loading and release. Nanogold is widely used and shows advantages in oncology treatment; however, it cannot encapsulate drugs directly and effectively like other nanovesicles or nanocages. The modified pillar[5]arenecan endow...

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Bibliographic Details
Published in:Chemistry : a European journal 2024-03, Vol.30 (13)
Main Authors: Jiang, Jianfeng, Su, Zhilian, He, Qin, Duan, Wengui, Huang, Yan, Liu, Luzhi
Format: Article
Language:English
Subjects:
Anticancer properties
Antitumor activity
Cancer therapies
Drug delivery
Online Access:Get full text
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Summary:Pillar[5]arene acts like an intelligent robot to efficiently regulate drug loading and release. Nanogold is widely used and shows advantages in oncology treatment; however, it cannot encapsulate drugs directly and effectively like other nanovesicles or nanocages. The modified pillar[5]arenecan endowed nanogold with excellent drug‐loading ability through a simple host–guest interaction, and successfully achieved the combination of DOX and GOX for cancer therapy. More information can be found in the Research Article by L. Liu and co‐workers (DOI: 10.1002/chem.202400007).
ISSN:0947-6539
1521-3765
DOI:10.1002/chem.202400526