Carbon Nanodots Obtained by Microwave Synthesis: Physical Properties and Assessment of Cytotoxicity on a Model of Glioblastoma and Embryonal Kidney In Vitro

Carbon nanodots (CNDs) produced by liquid-based synthesis methods are an example of a biocompatible, nontoxic nanomaterial with physical properties promising for various applications. In our work, CNDs were obtained from organic precursors by express synthesis in a microwave reactor followed by puri...

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Bibliographic Details
Published in:Physics of atomic nuclei 2023-12, Vol.86 (12), p.2724-2727
Main Authors: Kopylov, A. N., Musaeva, D. U., Kudelkina, V. V., Syui, A. V., Kosyreva, A. M., Alekseeva, A. I., Zakharkiv, A. Yu, Timoshenko, V. Yu
Format: Article
Language:English
Subjects:
Absorption spectroscopy
Biocompatibility
Carbon
Glioblastoma multiforme
Infrared spectroscopy
Isopropanol
Kidneys
Medical Physics and Biophysics
Nanomaterials
Particle and Nuclear Physics
Photoluminescence
Physical properties
Physics
Physics and Astronomy
Real property
Synthesis
Toxicity
Valuation
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Summary:Carbon nanodots (CNDs) produced by liquid-based synthesis methods are an example of a biocompatible, nontoxic nanomaterial with physical properties promising for various applications. In our work, CNDs were obtained from organic precursors by express synthesis in a microwave reactor followed by purification in isopropyl alcohol and were studied by transmission electron microscopy, infrared spectroscopy, and optical absorption spectroscopy in the ultraviolet–visible–near-infrared range, as well as photoluminescence. Cytotoxicity assessment was performed on in vitro models of glioblastoma and embryonic kidney. The obtained results indicate the prospects of the used method of CND synthesis in the production of nanomaterials for biomedical luminescent diagnostics.
ISSN:1063-7788
1562-692X
DOI:10.1134/S1063778823110261