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Carbon Nanodots Obtained by Microwave Synthesis: Physical Properties and Assessment of Cytotoxicity on a Model of Glioblastoma and Embryonal Kidney In Vitro

Carbon nanodots (CNDs) produced by liquid-based synthesis methods are an example of a biocompatible, nontoxic nanomaterial with physical properties promising for various applications. In our work, CNDs were obtained from organic precursors by express synthesis in a microwave reactor followed by puri...

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Published in:	Physics of atomic nuclei 2023-12, Vol.86 (12), p.2724-2727
Main Authors:	Kopylov, A. N., Musaeva, D. U., Kudelkina, V. V., Syui, A. V., Kosyreva, A. M., Alekseeva, A. I., Zakharkiv, A. Yu, Timoshenko, V. Yu
Format:	Article
Language:	English
Subjects:	Absorption spectroscopy Biocompatibility Carbon Glioblastoma multiforme Infrared spectroscopy Isopropanol Kidneys Medical Physics and Biophysics Nanomaterials Particle and Nuclear Physics Photoluminescence Physical properties Physics Physics and Astronomy Real property Synthesis Toxicity Valuation
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creator	Kopylov, A. N. Musaeva, D. U. Kudelkina, V. V. Syui, A. V. Kosyreva, A. M. Alekseeva, A. I. Zakharkiv, A. Yu Timoshenko, V. Yu
description	Carbon nanodots (CNDs) produced by liquid-based synthesis methods are an example of a biocompatible, nontoxic nanomaterial with physical properties promising for various applications. In our work, CNDs were obtained from organic precursors by express synthesis in a microwave reactor followed by purification in isopropyl alcohol and were studied by transmission electron microscopy, infrared spectroscopy, and optical absorption spectroscopy in the ultraviolet–visible–near-infrared range, as well as photoluminescence. Cytotoxicity assessment was performed on in vitro models of glioblastoma and embryonic kidney. The obtained results indicate the prospects of the used method of CND synthesis in the production of nanomaterials for biomedical luminescent diagnostics.
doi_str_mv	10.1134/S1063778823110261
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subjects	Absorption spectroscopy Biocompatibility Carbon Glioblastoma multiforme Infrared spectroscopy Isopropanol Kidneys Medical Physics and Biophysics Nanomaterials Particle and Nuclear Physics Photoluminescence Physical properties Physics Physics and Astronomy Real property Synthesis Toxicity Valuation
title	Carbon Nanodots Obtained by Microwave Synthesis: Physical Properties and Assessment of Cytotoxicity on a Model of Glioblastoma and Embryonal Kidney In Vitro
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