Comparative effectiveness of paravertebral Ozone injection and caudal epidural steroid-hyaluronidase injection in lumbosacral spinal stenosis

Lumbosacral spinal stenosis (LSS) is the narrowing of the lumbar spinal canal. LSS usually happens in older people who do not have the proper physical condition to undergo surgery. Therefore, minimally invasive methods such as Ozone therapy and epidural injection can be used in these patients. The o...

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Bibliographic Details
Published in:British journal of neurosurgery 2024-04, Vol.ahead-of-print (ahead-of-print), p.1-6
Main Authors: Parvin, Reyhaneh, Farpour, Hamid Reza, Khoshnazar, Sana, Jahromi, Leila sadat Mohamadi
Format: Article
Language:English
Subjects:
Aged
Back Pain
Epidural
epidural injection
Humans
hyaluronidase
Hyaluronoglucosaminidase - pharmacology
Hyaluronoglucosaminidase - therapeutic use
Injections, Epidural - methods
Lumbar Vertebrae
Lumbosacral spinal stenosis
ozone
Ozone - pharmacology
Ozone - therapeutic use
Spinal stenosis
Spinal Stenosis - complications
Spinal Stenosis - drug therapy
Spinal Stenosis - surgery
steroid
Steroids
Steroids - pharmacology
Steroids - therapeutic use
Treatment Outcome
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Summary:Lumbosacral spinal stenosis (LSS) is the narrowing of the lumbar spinal canal. LSS usually happens in older people who do not have the proper physical condition to undergo surgery. Therefore, minimally invasive methods such as Ozone therapy and epidural injection can be used in these patients. The objective this study was to compare the effect of caudal epidural steroid-hyaluronidase injection with paravertebral intramuscular Ozone injection on reducing pain in patients with LSS. A total of 30 patients suffering from LSS randomized to two groups. Group A (n = 15) received three paravertebral intramuscular infiltrations of the Ozone, Group B (n = 15) received a caudal epidural injection of steroid-hyaluronidase. The effects of the interventions were evaluated by measuring Visual analog scale (VAS), Oswestry Disability index (ODI), Quebec Back Pain Disability (QBPDS) and Roland Morris low back pain questionnaire (RMQ) before the interventions and at 2 weeks, 4 weeks, and 8 weeks after the interventions. Within-group changes showed significant improvement in VAS, ODI, RMQ, and QBPDS scores in both groups from pre-treatment to end of follow-up (all p 
ISSN:0268-8697
1360-046X
DOI:10.1080/02688697.2021.1885626