Iron-catalyzed C(sp3)–H phosphorylation via photoinduced LMCT

Alkylphosphines demonstrate excellent performance as ligands, catalysts and reagents based on their strong electron-donating properties. However, current methods for synthesizing alkylphosphines are limited to nucleophilic substitution reactions of air-sensitive organometallic reagents. Herein, we r...

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Bibliographic Details
Published in:Organic chemistry frontiers an international journal of organic chemistry 2024-03, Vol.11 (7), p.2027-2032
Main Authors: Liu, Hongchi, Wang, Kaifang, Ye, Sunfeng, Zhu, Qiming, Huang, Hanmin
Format: Article
Language:English
Subjects:
Catalysts
Charge transfer
Chemical bonds
Iron
Ligands
Phosphorylation
Reagents
Substitution reactions
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Summary:Alkylphosphines demonstrate excellent performance as ligands, catalysts and reagents based on their strong electron-donating properties. However, current methods for synthesizing alkylphosphines are limited to nucleophilic substitution reactions of air-sensitive organometallic reagents. Herein, we report an iron-catalyzed C(sp3)–H phosphorylation enabled by a photoinduced ligand-to-metal charge transfer (LMCT) process, allowing a straightforward synthesis of alkylphosphines from readily accessible chlorophosphines and diverse compounds containing C(sp3)–H bonds.
ISSN:2052-4110
2052-4110
DOI:10.1039/d3qo02121a