Influence of the Duration of Circadian Rhythm Dis-Turbance by Light Exposure on the Morphology of the Liver of Laboratory Rats

We studied the effect of long-term constant light exposure on the severity and reversibility of morphological changes in the liver of laboratory rats. Modeling of light exposure was carried out by means of 24 h exposure to artificial light (in the daytime—300 lk, at night—500 lk). During the study w...

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Bibliographic Details
Published in:Optics and spectroscopy 2023-10, Vol.131 (10), p.1058-1062
Main Authors: Pakhomy, S. S., Zlobina, O. V., Bugaeva, I. O., Maslyakova, G. N., Ivanov, A. N., Moskvina, A. O.
Format: Article
Language:English
Subjects:
Circadian rhythms
Exposure
Lasers
Liver
Morphology
Natural lighting
Optical Devices
Optics
Photonics
Physics
Physics and Astronomy
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Summary:We studied the effect of long-term constant light exposure on the severity and reversibility of morphological changes in the liver of laboratory rats. Modeling of light exposure was carried out by means of 24 h exposure to artificial light (in the daytime—300 lk, at night—500 lk). During the study we found that morphological changes in the liver were represented by damage to the parenchyma and circulatory disorders, the degree of which increased with increasing duration of exposure. After providing natural light in the laboratory, gradual recovery of the morphological structure of the organ was observed, which indicates the reversibility of the changes detected.
ISSN:0030-400X
1562-6911
DOI:10.1134/S0030400X2310017X