Evaluation of intracranial stereotactic treatment plans: a comparison study of CyberKnife and TrueBeam systems

Background:Stereotactic radiotherapy (SRT) for patients with intracranial tumours are delivered using a dedicated platform or a conventional linear accelerator with a flattening filter-free beam.Materials and methods:This study compares treatment plans with intracranial tumours. A total of 29 patien...

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Bibliographic Details
Published in:Journal of radiotherapy in practice 2024-04, Vol.23, Article e12
Main Authors: Shahban, Muhammad, Rizwan, Muhammad Tariq, Nazia, Neelam Shahzadi, Saeed, Ur Rehman, Humera, Mehmood, Faheem, Muhammad
Format: Article
Language:English
Subjects:
Brain stem
Conformity
Dosimetry
Homogeneity
Original Article
Patients
Planning
Radiation therapy
Radiosurgery
Tumors
Visual pathways
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Summary:Background:Stereotactic radiotherapy (SRT) for patients with intracranial tumours are delivered using a dedicated platform or a conventional linear accelerator with a flattening filter-free beam.Materials and methods:This study compares treatment plans with intracranial tumours. A total of 29 patients were treated on CyberKnife and planned using the Accuray Precision. The same structure sets ws then exported to Varian Eclipse, and plans were made using a 6 MV FFF beam. Both plans were compared for parameters of target coverage, homogeneity index (HI), new conformity index (nCI), gradient index, selectivity index (SI), volumetric and OAR doses.Results:The treatment plans made for CyberKnife exhibit better results in terms of nCI (1·168 ± 0·08 versus 1·173 ± 0·077), SI (0·885 ± 0·05 versus 0·877 ± 0·05) and GI (3·64 ± 0·5 versus 4·45 ± 1·25), while HI values are better for TrueBeam. For OAR doses, in 65·5% and 72% of treatment plans, brainstem and optic pathways received lower doses on CyberKnife, respectively. In terms of dose spillage, Truebeam plans are better for very low doses (V5%), while for V10%, V20% and V50% CyberKnife plans are better.Conclusion:CyberKnife is a better modality for the delivery of SRS/SRT to intracranial tumours except for dose homogeneity where TrueBeam offered better results.
ISSN:1460-3969
1467-1131
DOI:10.1017/S1460396924000104