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Fluoride exposure among children with different blood groups at Kolar district, Karnataka, India

Fluoride is present naturally in water at < 1.5 ppm and it is considered to be essential for dental and bone enamel mineralization forming fluorapatite. Chronic exposure (> 2ppm) is considered to be toxic and it leads to fluorosis. Fluoride in minor quantities is excreted through sweat, saliva...

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Bibliographic Details
Published in:Bioinformation 2024-03, Vol.20 (3), p.234
Main Authors: Shashidhar, Kurpad Nagaraj, Hemalatha, Anantharamaiah, Munilakshmi, Uppalamethi, Rose, Paramaturi Sharon, Meghanath, Muthyala
Format: Article
Language:English
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Summary:Fluoride is present naturally in water at < 1.5 ppm and it is considered to be essential for dental and bone enamel mineralization forming fluorapatite. Chronic exposure (> 2ppm) is considered to be toxic and it leads to fluorosis. Fluoride in minor quantities is excreted through sweat, saliva and feaces. Kidneys are the major route of excretion of fluoride and are thus it is the primary organ to be affected. Therefore, it is of interest to assess urinary fluoride among school children with different blood groups at Kolar district, Karnataka, India. Study was conducted in 155 subjects, aged 16-17 years. Data shows that blood group B has high risk of effecting by fluorosis (mean value of urine fluoride = 1.11). However, subjects with negative blood groups are least affected by fluorosis (mean value of urine fluoride =0.30). However, a larger population study is required for validation.
ISSN:0973-8894
0973-2063
DOI:10.6026/973206300200208