Miller-Fisher Syndrome Following Influenza A Infection

Miller-Fisher syndrome (MFS), characterized by ophthalmoplegia, ataxia, and areflexia, is a Guillain-Barré syndrome (GBS) variant. It is well-known that the causative antibody for MFS is anti-GQ1b antibody. This report describes a rare case of MFS with not only anti-GQ1b antibodies but also anti-GT1...

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Bibliographic Details
Published in:Curēus (Palo Alto, CA) CA), 2024-03, Vol.16 (3), p.e56064
Main Authors: Mitsuhashi, Shiho, Suzuki, Asuka, Hayashi, Koji, Sato, Mamiko, Nakaya, Yuka, Takaku, Naoko, Kobayashi, Yasutaka
Format: Article
Language:English
Subjects:
Antibodies
Ataxia
Campylobacter
Case reports
Cerebrospinal fluid
Diplopia
Eye movements
Fever
Guillain-Barre syndrome
Hospitals
Immunoglobulins
Infections
Influenza
Pathogens
Proteins
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Summary:Miller-Fisher syndrome (MFS), characterized by ophthalmoplegia, ataxia, and areflexia, is a Guillain-Barré syndrome (GBS) variant. It is well-known that the causative antibody for MFS is anti-GQ1b antibody. This report describes a rare case of MFS with not only anti-GQ1b antibodies but also anti-GT1a antibodies following Influenza A infection. The patient, a 47-year-old woman, contracted Influenza A three weeks before admission. She complained of double vision followed by areflexia, ataxia in the four extremities, and complete gaze palsy. She was treated with intravenous methylprednisolone pulse and intravenous immunoglobulin therapies. Her neurological symptoms were recovered after these immunotherapies.
ISSN:2168-8184
2168-8184
DOI:10.7759/cureus.56064