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Selective Organ‐Targeting Hafnium Oxide Nanoparticles with Multienzyme‐Mimetic Activities Attenuate Radiation‐Induced Tissue Damage (Adv. Mater. 19/2024)
Organ‐Targeting Radioprotective NanozymesUnlike commonly known radioenhancing similars, rationally designed HfO2 nanoparticles herein are surprisingly radioprotective and capable of selectively targeting top vulnerable normal organs to counteract off‐target toxicity during radiotherapy. Under CT ima...
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| Published in: | Advanced materials (Weinheim) 2024-05, Vol.36 (19) |
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| Main Authors: | , , , , , , , , , , , |
| Format: | Article |
| Language: | English |
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| container_issue | 19 |
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| container_title | Advanced materials (Weinheim) |
| container_volume | 36 |
| creator | Liu, Dingxin Cao, Fei Xu, Zhifeng Zhao, Chunhua Liu, Zekun Pang, Jiadong Liu, Ze‐Xian Moghiseh, Mahdieh Butler, Anthony Liang, Shaoxia Fan, Weijun Yang, Jiang |
| description | Organ‐Targeting Radioprotective NanozymesUnlike commonly known radioenhancing similars, rationally designed HfO2 nanoparticles herein are surprisingly radioprotective and capable of selectively targeting top vulnerable normal organs to counteract off‐target toxicity during radiotherapy. Under CT image guidance, the multienzyme‐mimetic agents can alleviate DNA damage and inflammation in mouse and rabbit models upon hazardous radiation exposure, resulting in prolonged survival. More details can be found in article number 2308098 by Weijun Fan, Jiang Yang, and co‐workers. |
| doi_str_mv | 10.1002/adma.202470149 |
| format | article |
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| identifier | ISSN: 0935-9648 |
| ispartof | Advanced materials (Weinheim), 2024-05, Vol.36 (19) |
| issn | 0935-9648 1521-4095 |
| language | eng |
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| source | Wiley-Blackwell Read & Publish Collection |
| subjects | Computed tomography Hafnium oxide Nanoparticles Radiation damage Radiation effects Radiation therapy |
| title | Selective Organ‐Targeting Hafnium Oxide Nanoparticles with Multienzyme‐Mimetic Activities Attenuate Radiation‐Induced Tissue Damage (Adv. Mater. 19/2024) |
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