Non-enzymatic determination of hydrogen peroxide in milk samples using Graphite oxide/Nafion/Azure A modified electrode

    A novel non-enzymatic electrochemical sensor was developed with high selectivity and sensitivity for detecting biologically significant hydrogen peroxide (H 2 O 2 ). The sensor utilized an electrode modified with graphite oxide/Nafion/Azure A (GO/Nf/AzA) fabricated by simple chemical adsorption...

Full description

Saved in:
Bibliographic Details
Published in:Ionics 2024-05, Vol.30 (5), p.2869-2880
Main Authors: Priya, Chandrasekaran, Anuja, Sriraman, Devendiran, Mani, Babu, Rajendran Suresh, Narayanan, Sangilimuthu Sriman
Format: Article
Language:English
Subjects:
Charge transfer
Chemical sensors
Chemistry
Chemistry and Materials Science
Condensed Matter Physics
Electrical measurement
Electrochemical analysis
Electrochemistry
Electrodes
Electron transfer
Electrons
Energy Storage
Graphite
Hydrogen peroxide
Optical and Electronic Materials
Parameter modification
Renewable and Green Energy
Sensitivity
Systems analysis
Voltammetry
Citations: Items that this one cites
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:    A novel non-enzymatic electrochemical sensor was developed with high selectivity and sensitivity for detecting biologically significant hydrogen peroxide (H 2 O 2 ). The sensor utilized an electrode modified with graphite oxide/Nafion/Azure A (GO/Nf/AzA) fabricated by simple chemical adsorption method. The incorporation of AzA into the GO/Nf matrix was verified through UV–Vis and FTIR spectroscopy. Electrochemical investigations via cyclic voltammetry and differential pulse voltammetry elucidated the modified electrode's properties. Optimization of experimental parameters, including pH and scan rates, enhanced its electrochemical behavior. Cyclic voltammetry analysis revealed an apparent electron transfer rate constant ( K s ) of 1.14 cm/s and a charge transfer coefficient ( α ) of 0.74. Compared to the bare graphite electrode, the modified electrode exhibited significantly higher current densities in response to H 2 O 2 with reduced overvoltage. The reduction peak currents for H 2 O 2 demonstrated a linear correlation with concentrations ranging from 1.3 × 10 −6  M to 3.6 × 10 −3  M, with a detection limit of 4.3 × 10 −7  M (S/N = 3). Notably, the proposed modified electrode displayed excellent sensitivity and selectivity, presenting a promising avenue for H 2 O 2 determination. In amperometric methods, it showcased stable and rapid responses, indicating potential for application in flow system analysis. Real sample analysis involving two distinct milk samples validated the electrodes' good recovery capabilities. Graphical Abstract
ISSN:0947-7047
1862-0760
DOI:10.1007/s11581-024-05470-z