Characterization of the chemical and structural modifications induced by X rays on the HEMA based polymer gel

The use of polymer gels in the radiation dosimetry field is rapidly increasing due to the possibility of 3 dimensional (3D) dosimetry. The aim of this study is to produce a new polymer gel with high dose sensitivity. This involved the production of polymer gel compositions containing different perce...

Full description

Saved in:
Bibliographic Details
Published in:Journal of instrumentation 2024-05, Vol.19 (5), p.P05055
Main Authors: Alkan, Türkan, Seki, Yoldaş, Yurt, Ayşegül
Format: Article
Language:English
Subjects:
Crosslinking
Degree of polymerization
Dosimeters
Dosimetry
Dosimetry concepts and apparatus
Electron microscopes
Ethylene glycol
Fourier transforms
Infrared analysis
Magnetic resonance imaging
MRI (whole body, cardiovascular, breast, others), MR-angiography (MRA)
Polyhydroxyethyl methacrylate
Polymer gels
Polymers
Radiation
Radiation damage evaluation methods
Radiation dosage
Radiation therapy
Radiotherapy concepts
Citations: Items that this one cites
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:The use of polymer gels in the radiation dosimetry field is rapidly increasing due to the possibility of 3 dimensional (3D) dosimetry. The aim of this study is to produce a new polymer gel with high dose sensitivity. This involved the production of polymer gel compositions containing different percentages of 2-hydroxyethyl methacrylate (HEMA) monomer and Di(ethylene glycol) dimethacrylate (DEGDMA) and 1-Vinyl-2-pyrrolidinone (VP) crosslinkers and these gels were irradiated with radiation dose between 0.5 Gy to 11 Gy, using 6 MV X-ray energy of the medical linear accelerator. The degree of polymerization was assessed by using magnetic resonance imaging (MRI) based on the R 2 -dose response. Then, Fourier Transform Infrared Spectroscopy (FTIR) analysis and Scanning Electron Microscope (SEM) images of the gels were taken. Polymer gels consisting of DEGDMA as crosslinker and Tetrakis (Hydroxymethyl) phosphonium chloride (THPC) as antioxidant were found to have a potential for use in radiation therapy dosimeter. The concentration of HEMA showing the most effective dose response was identified as 12 wt%. It was found that HEMA polymer gels containing DEGDMA crosslinker provide a better dose response than HEMA and HEMA-VP normoxic polymer gels.
ISSN:1748-0221
1748-0221
DOI:10.1088/1748-0221/19/05/P05055