Effect of Siphon Morphology on the Risk of C7 Segment Aneurysm Formation

PurposeTortuosity of the internal carotid artery (ICA) is associated with intracranial aneurysms (IAs). The siphon is the most curved segment of the ICA, but its morphology has controversial effects on IAs. This study aimed to explore the morphometric features of the siphon and the potential hemodyn...

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Bibliographic Details
Published in:Clinical neuroradiology (Munich) 2024-06, Vol.34 (2), p.485-494
Main Authors: Wang, Ying, Chen, Bo, Song, Laixin, Li, Yuzhe, Xu, Ming, Huang, Tianxiang, Zeng, Feiyue
Format: Article
Language:English
Subjects:
Aneurysms
Hemodynamics
Morphology
Veins & arteries
Online Access:Get full text
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Summary:PurposeTortuosity of the internal carotid artery (ICA) is associated with intracranial aneurysms (IAs). The siphon is the most curved segment of the ICA, but its morphology has controversial effects on IAs. This study aimed to explore the morphometric features of the siphon and the potential hemodynamic mechanisms that may affect C7 aneurysm formation.MethodsIn this study 32 patients with C7 aneurysms diagnosed at Xiangya Hospital between 2019 and 2021 and 32 control subjects were enrolled after propensity score matching. Computed tomography angiography (CTA) images were acquired to measure morphologic features, and then, by combining clinical data, simplified carotid siphon models were constructed, and computational fluid dynamics (CFD) analysis was performed.ResultsThe presence of C7 aneurysms was associated with the height of the C4–C6 curved arteries (odds ratio [OR] 0.028, 95% confidence interval [CI] 0.003–0.201; P 
ISSN:1869-1439
1869-1447
DOI:10.1007/s00062-024-01394-3