Recent advances in discovery and biosynthesis of natural products from myxobacteria: an overview from 2017 to 2023

Covering: 2017.01 to 2023.11 Natural products biosynthesized by myxobacteria are appealing due to their sophisticated chemical skeletons, remarkable biological activities, and intriguing biosynthetic enzymology. This review aims to systematically summarize the advances in the discovery methods, new...

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Bibliographic Details
Published in:Natural product reports 2024-06, Vol.41 (6), p.95-934
Main Authors: Wang, Chao-Yi, Hu, Jia-Qi, Wang, De-Gao, Li, Yue-Zhong, Wu, Changsheng
Format: Article
Language:English
Subjects:
Biological Products - chemistry
Biological Products - metabolism
Biosynthesis
Biosynthetic Pathways
Drug Discovery
Enzymology
Molecular Structure
Myxococcales - chemistry
Myxococcales - metabolism
Natural products
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Summary:Covering: 2017.01 to 2023.11 Natural products biosynthesized by myxobacteria are appealing due to their sophisticated chemical skeletons, remarkable biological activities, and intriguing biosynthetic enzymology. This review aims to systematically summarize the advances in the discovery methods, new structures, and bioactivities of myxobacterial NPs reported in the period of 2017-2023. In addition, the peculiar biosynthetic pathways of several structural families are also highlighted. This review presents a comprehensive overview of recent advances in the discovery methodologies, new structures, bioactivities, and unique biosynthetic logics of myxobacterial natural products reported from January 2017 to November 2023.
ISSN:0265-0568
1460-4752
1460-4752
DOI:10.1039/d3np00062a