Prognostic scores for predicting clinical outcomes in upper gastrointestinal bleeding

Background and aimsThis study aimed to determine the performance of AIMS65, Rockall score, and Glasgow-Blatchford score (GBS) in patients presenting with upper gastrointestinal bleeding (UGIB) and to compare results between patients with nonvariceal UGIB (NVUGIB) and variceal UGIB (VUGIB).MethodsWe...

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Bibliographic Details
Published in:Egyptian Liver Journal 2024-07, Vol.14 (1), p.49-17
Main Authors: Khatana, Gaurav, K, Sunil Kumar, Kolassery, Sandesh, Sebastian, Saji, Joseph, Deni, Muraleedharanpillai, Ramu, Joseph, Tony, V, Nithya, Unnikrishnan, Lal Krishna, Rony, Gino
Format: Article
Language:English
Subjects:
Age
AIMS65 score
Blood pressure
Blood transfusions
Cardiovascular disease
Clinical outcomes
Coma
Comorbidity
Data collection
Embolization
Endoscopy
Females
Glasgow-Blatchford score
Heart rate
Hematemesis
Hemoglobin
Hospitals
Intervention
Mortality
Patients
Rockall score
Ulcers
Upper gastrointestinal bleeding
Vomiting
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Summary:Background and aimsThis study aimed to determine the performance of AIMS65, Rockall score, and Glasgow-Blatchford score (GBS) in patients presenting with upper gastrointestinal bleeding (UGIB) and to compare results between patients with nonvariceal UGIB (NVUGIB) and variceal UGIB (VUGIB).MethodsWe conducted a single-center prospective cohort study between December 2021 and December 2022. A total of 400 patients who met the inclusion criteria were included in the study, out of which 232 patients (58%) had NVUGIB and 168 patients (42%) had VUGIB. Receiver operating characteristic curve analysis was performed for all outcomes for comparison.ResultsOf the total of 400 patients with UGIB, 232 patients (58%) had NVUGIB, and 168 patients (42%) had VUGIB. The present study showed that GBS (AUROC 0.729, 95% CI: 0.598–0.859, p = 0.001) and RS (AUROC 0.693, 95% CI: 0.579–0.807, p = 0.005) but not AIMS65 (AUROC, 0.545, 95% CI: 0.412–0.679, p = 0.500) predicted in-hospital and overall 6-week mortality in patients with UGIB. All the three scores predicted need for blood transfusion and poor composite outcomes (p 
ISSN:2090-6218
2090-6226
DOI:10.1186/s43066-024-00357-0