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The Effect of Cerebral White Matter Lesions on Walking Time & Vascular Risk Factors
Introduction: White matter lesions are common neurological diseases in the elderly. In this study, we aimed to investigate the impact of cerebral white matter lesions on walking time and daily living activities in the elderly population. Methods: A total of 82 individuals, including 40 healthy volun...
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Published in: | Dicle tıp dergisi 2024-06, Vol.51 (2), p.191-198 |
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description | Introduction: White matter lesions are common neurological diseases in the elderly. In this study, we aimed to investigate the impact of cerebral white matter lesions on walking time and daily living activities in the elderly population. Methods: A total of 82 individuals, including 40 healthy volunteers and 42 age and sex-matched patients, were enrolled in this study. Magnetic resonance imaging findings were recorded based on the Fazekas Staging System. Risk factors potentially predisposing individuals to white matter lesions were documented through laboratory testing. Additionally, atherothrombotic plaque formations and stenosis were graded using Carotid and Vertebral Artery Doppler Ultrasonography in patients with white matter lesions. The Lawton Instrumental Activities of Daily Living Scale, Mini-Mental State Examination, and the Timed Up & Go Test were administered to both the patient and control groups to assess daily living activities and cognitive functions. Results: The results of this research showed that as the percentage of stenosis increased in Carotid and Vertebral Artery Doppler Ultrasonography, there were corresponding decreases in Lawton Instrumental Activities of Daily Living Scale scores, haemoglobin and hematocrit values while fasting blood glucose and homocysteine levels increased as expected. Furthermore, significant differences were observed in the Timed Up & Go Test in advanced stages when evaluated according to the Fazekas Staging System. Conclusion: Our study indicated that white matter lesions do not significantly affect daily living activities but prolong the walking time in elderly individuals. |
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In this study, we aimed to investigate the impact of cerebral white matter lesions on walking time and daily living activities in the elderly population. Methods: A total of 82 individuals, including 40 healthy volunteers and 42 age and sex-matched patients, were enrolled in this study. Magnetic resonance imaging findings were recorded based on the Fazekas Staging System. Risk factors potentially predisposing individuals to white matter lesions were documented through laboratory testing. Additionally, atherothrombotic plaque formations and stenosis were graded using Carotid and Vertebral Artery Doppler Ultrasonography in patients with white matter lesions. The Lawton Instrumental Activities of Daily Living Scale, Mini-Mental State Examination, and the Timed Up & Go Test were administered to both the patient and control groups to assess daily living activities and cognitive functions. Results: The results of this research showed that as the percentage of stenosis increased in Carotid and Vertebral Artery Doppler Ultrasonography, there were corresponding decreases in Lawton Instrumental Activities of Daily Living Scale scores, haemoglobin and hematocrit values while fasting blood glucose and homocysteine levels increased as expected. Furthermore, significant differences were observed in the Timed Up & Go Test in advanced stages when evaluated according to the Fazekas Staging System. Conclusion: Our study indicated that white matter lesions do not significantly affect daily living activities but prolong the walking time in elderly individuals.</description><identifier>ISSN: 1300-2945</identifier><identifier>EISSN: 1308-9889</identifier><identifier>DOI: 10.5798/dicletip.1501114</identifier><language>eng</language><publisher>Diyarbakir: Dicle University</publisher><subject>Activities of daily living ; Alzheimer's disease ; Blood pressure ; Body mass index ; Cardiovascular disease ; Constipation ; Coronary vessels ; Diabetes ; Disease prevention ; Homocysteine ; Hypertension ; Laboratories ; Magnetic resonance imaging ; Older people ; Outpatient care facilities ; Patients ; Risk factors ; Statistical analysis ; Ultrasonic imaging ; Variance analysis ; Vein & artery diseases</subject><ispartof>Dicle tıp dergisi, 2024-06, Vol.51 (2), p.191-198</ispartof><rights>2024. This work is published under https://creativecommons.org/licenses/by-nc/4.0/ (the “License”). Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License.</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><cites>FETCH-LOGICAL-c1114-a79b39b589de5b1fb6b2303af933d3df3a4732deed26c92415f342a1fdfb6a3f3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.proquest.com/docview/3075407787/fulltextPDF?pq-origsite=primo$$EPDF$$P50$$Gproquest$$Hfree_for_read</linktopdf><linktohtml>$$Uhttps://www.proquest.com/docview/3075407787?pq-origsite=primo$$EHTML$$P50$$Gproquest$$Hfree_for_read</linktohtml><link.rule.ids>314,780,784,25753,27924,27925,37012,44590,74998</link.rule.ids></links><search><creatorcontrib>Erdem, Miray</creatorcontrib><creatorcontrib>Ozdogru, Derya</creatorcontrib><creatorcontrib>Tantik Pak, Aygül</creatorcontrib><creatorcontrib>Söker, Elif Banu</creatorcontrib><creatorcontrib>Arlıer, Zülfikar</creatorcontrib><title>The Effect of Cerebral White Matter Lesions on Walking Time & Vascular Risk Factors</title><title>Dicle tıp dergisi</title><description>Introduction: White matter lesions are common neurological diseases in the elderly. In this study, we aimed to investigate the impact of cerebral white matter lesions on walking time and daily living activities in the elderly population. Methods: A total of 82 individuals, including 40 healthy volunteers and 42 age and sex-matched patients, were enrolled in this study. Magnetic resonance imaging findings were recorded based on the Fazekas Staging System. Risk factors potentially predisposing individuals to white matter lesions were documented through laboratory testing. Additionally, atherothrombotic plaque formations and stenosis were graded using Carotid and Vertebral Artery Doppler Ultrasonography in patients with white matter lesions. The Lawton Instrumental Activities of Daily Living Scale, Mini-Mental State Examination, and the Timed Up & Go Test were administered to both the patient and control groups to assess daily living activities and cognitive functions. Results: The results of this research showed that as the percentage of stenosis increased in Carotid and Vertebral Artery Doppler Ultrasonography, there were corresponding decreases in Lawton Instrumental Activities of Daily Living Scale scores, haemoglobin and hematocrit values while fasting blood glucose and homocysteine levels increased as expected. Furthermore, significant differences were observed in the Timed Up & Go Test in advanced stages when evaluated according to the Fazekas Staging System. Conclusion: Our study indicated that white matter lesions do not significantly affect daily living activities but prolong the walking time in elderly individuals.</description><subject>Activities of daily living</subject><subject>Alzheimer's disease</subject><subject>Blood pressure</subject><subject>Body mass index</subject><subject>Cardiovascular disease</subject><subject>Constipation</subject><subject>Coronary vessels</subject><subject>Diabetes</subject><subject>Disease prevention</subject><subject>Homocysteine</subject><subject>Hypertension</subject><subject>Laboratories</subject><subject>Magnetic resonance imaging</subject><subject>Older people</subject><subject>Outpatient care facilities</subject><subject>Patients</subject><subject>Risk factors</subject><subject>Statistical analysis</subject><subject>Ultrasonic imaging</subject><subject>Variance analysis</subject><subject>Vein & artery diseases</subject><issn>1300-2945</issn><issn>1308-9889</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2024</creationdate><recordtype>article</recordtype><sourceid>PIMPY</sourceid><recordid>eNo1kE1PAyEURYnRxFrduyQxcTcVBhiGpWnqR1JjotUuCQMPSzudqUAX_ntbW1fvLk7ufTkIXVMyElLVdy7YFnLYjKgglFJ-ggaUkbpQda1O_zIpSsXFObpIaUlIVXHFB-h9tgA88R5sxr3HY4jQRNPi-SJkwC8mZ4h4Cin0XcJ9h-emXYXuC8_CGvAt_jTJblsT8VtIK_xgbO5jukRn3rQJro53iD4eJrPxUzF9fXwe308Lu3-wMFI1TDWiVg5EQ31TNSUjzHjFmGPOM8MlKx2AKyurSk6FZ7w01LsdaphnQ3Rz6N3E_nsLKetlv43dblIzIgUnUtZyR5EDZWOfUgSvNzGsTfzRlOi9Ov2vTh_VsV9-RWLW</recordid><startdate>20240614</startdate><enddate>20240614</enddate><creator>Erdem, Miray</creator><creator>Ozdogru, Derya</creator><creator>Tantik Pak, Aygül</creator><creator>Söker, Elif Banu</creator><creator>Arlıer, Zülfikar</creator><general>Dicle University</general><scope>AAYXX</scope><scope>CITATION</scope><scope>3V.</scope><scope>7X7</scope><scope>7XB</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>AZQEC</scope><scope>BENPR</scope><scope>CCPQU</scope><scope>DWQXO</scope><scope>EDSIH</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>K9.</scope><scope>M0S</scope><scope>PIMPY</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PRINS</scope></search><sort><creationdate>20240614</creationdate><title>The Effect of Cerebral White Matter Lesions on Walking Time & Vascular Risk Factors</title><author>Erdem, Miray ; Ozdogru, Derya ; Tantik Pak, Aygül ; Söker, Elif Banu ; Arlıer, Zülfikar</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c1114-a79b39b589de5b1fb6b2303af933d3df3a4732deed26c92415f342a1fdfb6a3f3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2024</creationdate><topic>Activities of daily living</topic><topic>Alzheimer's disease</topic><topic>Blood pressure</topic><topic>Body mass index</topic><topic>Cardiovascular disease</topic><topic>Constipation</topic><topic>Coronary vessels</topic><topic>Diabetes</topic><topic>Disease prevention</topic><topic>Homocysteine</topic><topic>Hypertension</topic><topic>Laboratories</topic><topic>Magnetic resonance imaging</topic><topic>Older people</topic><topic>Outpatient care facilities</topic><topic>Patients</topic><topic>Risk factors</topic><topic>Statistical analysis</topic><topic>Ultrasonic imaging</topic><topic>Variance analysis</topic><topic>Vein & artery diseases</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Erdem, Miray</creatorcontrib><creatorcontrib>Ozdogru, Derya</creatorcontrib><creatorcontrib>Tantik Pak, Aygül</creatorcontrib><creatorcontrib>Söker, Elif Banu</creatorcontrib><creatorcontrib>Arlıer, Zülfikar</creatorcontrib><collection>CrossRef</collection><collection>ProQuest Central (Corporate)</collection><collection>Health & Medical Collection</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>ProQuest Central (Alumni Edition)</collection><collection>ProQuest Central</collection><collection>ProQuest Central Essentials</collection><collection>ProQuest Central</collection><collection>ProQuest One Community College</collection><collection>ProQuest Central</collection><collection>Turkey Database</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Health & Medical Collection (Alumni Edition)</collection><collection>Publicly Available Content (ProQuest)</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>ProQuest Central China</collection><jtitle>Dicle tıp dergisi</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Erdem, Miray</au><au>Ozdogru, Derya</au><au>Tantik Pak, Aygül</au><au>Söker, Elif Banu</au><au>Arlıer, Zülfikar</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>The Effect of Cerebral White Matter Lesions on Walking Time & Vascular Risk Factors</atitle><jtitle>Dicle tıp dergisi</jtitle><date>2024-06-14</date><risdate>2024</risdate><volume>51</volume><issue>2</issue><spage>191</spage><epage>198</epage><pages>191-198</pages><issn>1300-2945</issn><eissn>1308-9889</eissn><abstract>Introduction: White matter lesions are common neurological diseases in the elderly. In this study, we aimed to investigate the impact of cerebral white matter lesions on walking time and daily living activities in the elderly population. Methods: A total of 82 individuals, including 40 healthy volunteers and 42 age and sex-matched patients, were enrolled in this study. Magnetic resonance imaging findings were recorded based on the Fazekas Staging System. Risk factors potentially predisposing individuals to white matter lesions were documented through laboratory testing. Additionally, atherothrombotic plaque formations and stenosis were graded using Carotid and Vertebral Artery Doppler Ultrasonography in patients with white matter lesions. The Lawton Instrumental Activities of Daily Living Scale, Mini-Mental State Examination, and the Timed Up & Go Test were administered to both the patient and control groups to assess daily living activities and cognitive functions. Results: The results of this research showed that as the percentage of stenosis increased in Carotid and Vertebral Artery Doppler Ultrasonography, there were corresponding decreases in Lawton Instrumental Activities of Daily Living Scale scores, haemoglobin and hematocrit values while fasting blood glucose and homocysteine levels increased as expected. Furthermore, significant differences were observed in the Timed Up & Go Test in advanced stages when evaluated according to the Fazekas Staging System. Conclusion: Our study indicated that white matter lesions do not significantly affect daily living activities but prolong the walking time in elderly individuals.</abstract><cop>Diyarbakir</cop><pub>Dicle University</pub><doi>10.5798/dicletip.1501114</doi><tpages>8</tpages><oa>free_for_read</oa></addata></record> |
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subjects | Activities of daily living Alzheimer's disease Blood pressure Body mass index Cardiovascular disease Constipation Coronary vessels Diabetes Disease prevention Homocysteine Hypertension Laboratories Magnetic resonance imaging Older people Outpatient care facilities Patients Risk factors Statistical analysis Ultrasonic imaging Variance analysis Vein & artery diseases |
title | The Effect of Cerebral White Matter Lesions on Walking Time & Vascular Risk Factors |
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