Autism treatment with magnetic stimulation: neurophysiological bases

Autism and Autism Spectrum Disorders are neurodevelopmental disorders. The critical periods of neurodevelopment end in the structural consolidation of a neuronal circuit and its connectivity. These periods are regulated by inhibitory interneurons that express the parvalbumin protein. The absence of...

Full description

Saved in:
Bibliographic Details
Published in:Acta Neurológica Colombiana 2018-01, Vol.34 (1), p.101
Main Authors: Castillo Castelblanco, Gabriel Augusto, Ramírez García, Sergio Francisco, Diana Jeannette Peñuela Novoa, Hernández Preciado, José Fernando
Format: Article
Language:Spanish
Subjects:
Autism
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Autism and Autism Spectrum Disorders are neurodevelopmental disorders. The critical periods of neurodevelopment end in the structural consolidation of a neuronal circuit and its connectivity. These periods are regulated by inhibitory interneurons that express the parvalbumin protein. The absence of parvalbumin in Autism leads to an imbalance of the excitation inhibition ratio. Hyperexcitability prevents adequate synchronization and connectivity with other brain regions. Transcraneal Magnetic Stimulation in Autism and ASD attempts to modify the neurophysiological abnormalities of the compromised circuits.
ISSN:0120-8748
2422-4022
DOI:10.22379/24224022185