A Case Report of Metformin Related Lactic Acidosis

Metformin is an oral antidiabetic drug of the biguanide classused in type 2 diabetic patients with normal renal function. The mortality rate is high in cases of lactic acidos is developing in metformin intoxication. In the emergency department, metformin intoxication should be considered in the diff...

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Published in:Journal of emergency medicine case reports 2023-06, Vol.14 (2), p.44-45
Main Authors: AKBAŞ, İlker, AKUFUK, Caner, YILMAZ, Muhammet Mustafa, KURT, Atilla Eren, COŞKUN, Fatih
Format: Article
Language:English
Subjects:
Acidosis
Anorexia
Case reports
Creatinine
Diabetes
Drug dosages
Emergency medical care
Glucose
Hematuria
Hemodialysis
Hypothermia
Internal medicine
Intoxication
Inventors
Kidney diseases
Medicine
Metabolism
Mortality
Nausea
Patients
Poisoning
Poisons
Vomiting
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creator AKBAŞ, İlker
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description Metformin is an oral antidiabetic drug of the biguanide classused in type 2 diabetic patients with normal renal function. The mortality rate is high in cases of lactic acidos is developing in metformin intoxication. In the emergency department, metformin intoxication should be considered in the differential diagnosis of patients whouse metformin and have high anion gap metabolic acidosis (lactic acidosis). The most important and effective treatment with early diagnosis is correction of metabolic acidosis with hemodialysis or hemofiltration methods, bicarbonate treatment, adjustment of blood glucose level. Cardiovascular system support therapy significantly reduces morbidity/mortality. In this case report, we present the early diagnosis and successful treatment of a patient with lactic acidosis due to metformin intoxication.
doi_str_mv 10.33706/jemcr.1294738
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subjects Acidosis
Anorexia
Case reports
Creatinine
Diabetes
Drug dosages
Emergency medical care
Glucose
Hematuria
Hemodialysis
Hypothermia
Internal medicine
Intoxication
Inventors
Kidney diseases
Medicine
Metabolism
Mortality
Nausea
Patients
Poisoning
Poisons
Vomiting
title A Case Report of Metformin Related Lactic Acidosis
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