Effects of gestational and pregestational diabetes mellitus on the foetal heart: a cross-sectional study

We examined the foetal cardiac structural and functional characteristics in diabetic pregnancies versus non-diabetic, healthy pregnancies. Between August 2015 and April 2016, 32 pregnant women with pregestational diabetes, 36 pregnant women with gestational diabetes, and 42 healthy pregnant women we...

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Bibliographic Details
Published in:Journal of obstetrics and gynaecology 2018-04, Vol.38 (3), p.408-412
Main Authors: Dervisoglu, Pinar, Kosecik, Mustafa, Kumbasar, Serkan
Format: Article
Language:English
Subjects:
Adult
Diabetes Mellitus, Type 1 - complications
Diabetes, Gestational - physiopathology
Diastole
diastolic dysfunction
Echocardiography
Female
Fetal Heart - diagnostic imaging
Fetal Heart - pathology
Fetal Heart - physiopathology
foetal echocardiography
Gestational Age
Gestational diabetes
Gestational diabetes mellitus
Humans
Hyperglycemia
Hyperglycemia - complications
Hypertrophy - etiology
Insulin - adverse effects
Insulin - therapeutic use
interventricular septum thickness
Preconception Care
Pregnancy
Pregnancy Complications - pathology
Pregnancy Complications - physiopathology
Tricuspid Valve - embryology
Tricuspid Valve - physiopathology
Ultrasonography, Prenatal - methods
Ventricular Septum - embryology
Ventricular Septum - pathology
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Summary:We examined the foetal cardiac structural and functional characteristics in diabetic pregnancies versus non-diabetic, healthy pregnancies. Between August 2015 and April 2016, 32 pregnant women with pregestational diabetes, 36 pregnant women with gestational diabetes, and 42 healthy pregnant women were scheduled to have foetal echocardiograms to assess cardiac structure and function. In the diabetic groups, the foetal interventricular septum (IVS) thickness was significantly greater than in non-diabetics (p 2 SD from normal. The peak velocity of tricuspid E, and the E/A ratio were significantly lower in the diabetic groups (p 
ISSN:0144-3615
1364-6893
DOI:10.1080/01443615.2017.1410536