Ovulation induction with clomiphene citrate or letrozole following laparoscopy in infertile women with minimal to mild endometriosis: a prospective randomised controlled trial

We conducted a prospective randomised controlled trial to explore the efficacy of clomiphene citrate (CC) and Letrozole (LTZ) for improving fecundity in infertile women with minimal to mild endometriosis after operative laparoscopy. We found that the ovulation rate of LTZ (88.7%) and CC (84.5%) were...

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Bibliographic Details
Published in:Journal of obstetrics and gynaecology 2022-02, Vol.42 (2), p.316-321
Main Authors: Zhou, Lu, Fu, Jing, Liu, Dong, Wang, Qiuyi, Chen, Hengxi, Yang, Shiyuan, Huang, Wei
Format: Article
Language:English
Subjects:
Birth rate
Clomiphene
clomiphene citrate
Endometriosis
Endometriosis - complications
Endometriosis - drug therapy
Endometriosis - surgery
Female
Fertility
Fertility Agents, Female
Humans
infertility
Infertility, Female - drug therapy
Infertility, Female - etiology
Laparoscopy
Letrozole
Ovulation
Ovulation Induction
Polycystic Ovary Syndrome
Pregnancy
Pregnancy Rate
Prospective Studies
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Summary:We conducted a prospective randomised controlled trial to explore the efficacy of clomiphene citrate (CC) and Letrozole (LTZ) for improving fecundity in infertile women with minimal to mild endometriosis after operative laparoscopy. We found that the ovulation rate of LTZ (88.7%) and CC (84.5%) were significantly higher than that of Control (70.5%) (p 
ISSN:0144-3615
1364-6893
DOI:10.1080/01443615.2021.1904224