Cytotoxicity and Compatibility of Polymeric Blend: Evaluation of the Cytotoxicity in Fibroblast Bovine Cells and Compatibility of Poly(ɛ-Caprolactone)/Poly(Methyl Methacrylate-co-Butyl Methacrylate) Blend Films

Blends between poly(ϵ-caprolactone) and poly(methyl methacrylate-co-butyl methacrylate) were prepared by solution blending in the presence of dichloromethane as solvent. The compatibility of the blends was studied by Fourier-transform infrared spectroscopy, Raman spectroscopy, micro-Raman imaging, a...

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Bibliographic Details
Published in:Polymer-plastics technology and engineering 2017-07, Vol.56 (10), p.1076-1083
Main Authors: Souza, Nelson Luis G. D., Munk, Michele, Brandão, Humberto M., de Oliveira, Luiz Fernando C.
Format: Article
Language:English
Subjects:
Biocompatibility
Carbonyl groups
Carbonyls
Cattle
Compatibility
cytotoxicity
Dichloromethane
Fibroblasts
Fourier transforms
Infrared analysis
Infrared spectroscopy
poly(methyl methacrylate-co-butyl methacrylate)
poly(ϵ-caprolactone)
Polycaprolactone
Polymer blends
Polymethyl methacrylate
Raman spectroscopy
Solution blending
Thermogravimetric analysis
Toxicity
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Summary:Blends between poly(ϵ-caprolactone) and poly(methyl methacrylate-co-butyl methacrylate) were prepared by solution blending in the presence of dichloromethane as solvent. The compatibility of the blends was studied by Fourier-transform infrared spectroscopy, Raman spectroscopy, micro-Raman imaging, and thermogravimetric analysis. Cytotoxicity assays were also performed to assess the feasibility of using such materials in veterinary devices. Based on results, we conclude that poly(ϵ-caprolactone) and poly(methyl methacrylate-co-butyl methacrylate)-form compatible blends owing to specific interactions between carbonyl groups of poly(methyl methacrylate-co-butyl methacrylate) and hydrogens present in the polymeric chain of poly(ϵ-caprolactone). Furthermore, these materials were not toxic to bovine fibroblasts, which supports their possible use in cattle veterinary devices.
ISSN:0360-2559
1525-6111
DOI:10.1080/03602559.2016.1253735