Comparison of Accelerated Corneal Collagen Cross-linking Methods

• Published in: Haydarpașa Numune Hastanesi tıp dergisi = The medical journal of Haydarpașa Numune Hospital 2021, Vol.61 (4), p.412
• Main Author: Yurttaşer Ocak, Serap
• Format: Article
• Language: English
• Subjects: Collagen; Cornea; Surgery; Topography; Ultraviolet radiation; Visual acuity
• ISSN: 1300-6363
• DOI: 10.14744/hnhj.2021.93798

[LANGUAGE= "English"] INTRODUCTION: Our aim in this study was to compare the results of accelerated collagen cross-linking (CXL) treatments on visual acuity and topographic parameters in cases with progressive keratoconus.METHODS: The cases with the diagnosis of progressive keratoconus between January 2015 and January 2018, who underwent accelerated CXL, were analyzed retrospectively. Subjects who received 9 mW/cm² ultraviolet A (UV-A) treatment for 10 min and were treated with 18 mW/cm2 UV-A for 5 min were included in the study. Uncorrected visual acuity (UCVA), Uncorrected visual acuity (BCVA), refractive value changes (spherical, cylindrical values), and corneal topography values obtained using the Sirius device at preoperative and postoperative 1st, 3rd, 6th and 12th months (K1, K2, Kmaximum, anterior elevation, posterior elevation) were compared statistically.RESULTS: A total of 80 eyes of 80 cases; 40 eyes treated with UV-A for 10 min and 40 eyes treated with UV-A for 5 min were included in the study. There was no difference between the two groups in terms of age and gender. There was a statistically significant increase in UCVA and BCVA (logMAR) values for both groups at the 6th and 12th months post-operatively when we compared the values before surgery (p0.05).DISCUSSION AND CONCLUSION: In cases of progressive keratoconus, 10-min 9 mW/cm² and 5-min 18 mW/cm² accelerated CXL methods showed similar results at the end of 1-year follow-up in terms of visual acuity improvement and topographic changes. Both methods seem to be effective in preventing keratoconus progression.[LANGUAGE= "Turkish"] GİRİŞ ve AMAÇ: Bu çalışmadaki amacımız, ilerleyici keratokonuslu olgularda hızlandırılmış kollajen çapraz bağlama (CXL) tedavilerinin görme keskinliği ve topografik parametreler üzerindeki sonuçlarını karşılaştırmaktır.YÖNTEM ve GEREÇLER: Ocak 2015-Ocak 2018 tarihleri arasında progresif keratokonus tanısı ile hızlandırılmış CXL uygulanan olgular retrospektif olarak değerlendirildi. Çalışmaya 10 dakika 9 mW/cm² Ultraviyole A (UV-A) tedavisi alan ve 18 mW/cm2 UV-A ile 5 dakika tedavi edilen olgular dahil edildi. Ameliyat öncesi ve ameliyat sonrası 1., 3., 6. ve 12. aylarda Sirius cihazı kullanılarak elde edilen düzeltilmemiş görme keskinliği