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Evaluation of HbA1c levels as probable diagnostic of depression symptoms in Mexican individuals with type 2 diabetes mellitus
Background Depression is present in individuals with type 2 diabetes mellitus. Objective We evaluated the sociodemographic, anthropometric, and clinical features of Mexican individuals with clinical depressive symptoms in order to identify predictors for depression symptoms; finally, we evaluated...
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| Published in: | International journal of diabetes in developing countries 2024-09, Vol.44 (3), p.585-591 |
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| Main Authors: | , , , , , , , , |
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| container_end_page | 591 |
| container_issue | 3 |
| container_start_page | 585 |
| container_title | International journal of diabetes in developing countries |
| container_volume | 44 |
| creator | Juárez-Rojop, Isela Esther Tovilla-Vidal, Gisselle López-Narváez, María Lilia Tovilla-Zárate, Carlos Alfonso Rodríguez-Sánchez, Esther González-Castro, Thelma Beatriz Fresán, Ana Ramírez-González, Dania Hernández-Díaz, Yazmín |
| description | Background
Depression is present in individuals with type 2 diabetes mellitus.
Objective
We evaluated the sociodemographic, anthropometric, and clinical features of Mexican individuals with clinical depressive symptoms in order to identify predictors for depression symptoms; finally, we evaluated if HbA1c levels could be used as a probable diagnostic of depressive symptoms in individuals with type 2 diabetes mellitus.
Methods
The population studied consisted of 376 Mexicans with diabetes who were interviewed to collect information about comorbidities and habits. The evaluation of depressive symptoms was performed using the Hamilton scale. For a possible clinical association between HbA1c levels and depressive symptoms, we performed chi-square tests (
χ
2
)/
t
tests. A multivariate logistic regression model with the backward conditional method was used to identify predictors of depressive symptoms. An ROC curve was plotted to assess the possible role of HbA1c as a diagnostic predictive test of depression symptoms.
Results
A total of 42.8% (
n
= 161) individuals showed clinical depressive symptoms. When comparing individuals with and without depression symptoms, those with depression symptoms showed higher levels of glucose and HbA1c; additionally, gender (
p
= 0.04), age (
p
= 0.006), HbA1c (
p
|
| doi_str_mv | 10.1007/s13410-023-01232-1 |
| format | article |
| fullrecord | <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_journals_3090926113</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>3090926113</sourcerecordid><originalsourceid>FETCH-LOGICAL-c270t-6da20695db157899b4e2993fa0c723b2c1f081dd22aba3fb94c0be31f94a5e5a3</originalsourceid><addsrcrecordid>eNp9kLFOwzAQhi0EEqXwAkyWmANnX9LUY1UVilTEArNlJ5fiKk1C7BQ68O64FImN6W74vv90P2PXAm4FQH7nBaYCEpCYgJAoE3HCRkKpaYJTlKdsBCrHBBXCObvwfgOQZXKCI_a12Jl6MMG1DW8rvrQzUfCadlR7bjzv-tYaWxMvnVk3rQ-uOGAldT15f5D8ftuFduu5a_gTfbrCNHEt3c6Vg4khHy688bDviMtDiKVAnm-prl0Y_CU7qyJEV79zzF7vFy_zZbJ6fnicz1ZJIXMIyaQ0EiYqK63I8qlSNiWpFFYGilyilYWoYCrKUkpjDVZWpQVYQlGp1GSUGRyzm2Nu_Od9IB_0ph36Jp7UCAqUnAiBkZJHquhb73uqdNe7ren3WoA-1KyPNetYs_6pWYso4VHyEW7W1P9F_2N9Az1ugbw</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>3090926113</pqid></control><display><type>article</type><title>Evaluation of HbA1c levels as probable diagnostic of depression symptoms in Mexican individuals with type 2 diabetes mellitus</title><source>Springer Link</source><creator>Juárez-Rojop, Isela Esther ; Tovilla-Vidal, Gisselle ; López-Narváez, María Lilia ; Tovilla-Zárate, Carlos Alfonso ; Rodríguez-Sánchez, Esther ; González-Castro, Thelma Beatriz ; Fresán, Ana ; Ramírez-González, Dania ; Hernández-Díaz, Yazmín</creator><creatorcontrib>Juárez-Rojop, Isela Esther ; Tovilla-Vidal, Gisselle ; López-Narváez, María Lilia ; Tovilla-Zárate, Carlos Alfonso ; Rodríguez-Sánchez, Esther ; González-Castro, Thelma Beatriz ; Fresán, Ana ; Ramírez-González, Dania ; Hernández-Díaz, Yazmín</creatorcontrib><description>Background
Depression is present in individuals with type 2 diabetes mellitus.
Objective
We evaluated the sociodemographic, anthropometric, and clinical features of Mexican individuals with clinical depressive symptoms in order to identify predictors for depression symptoms; finally, we evaluated if HbA1c levels could be used as a probable diagnostic of depressive symptoms in individuals with type 2 diabetes mellitus.
Methods
The population studied consisted of 376 Mexicans with diabetes who were interviewed to collect information about comorbidities and habits. The evaluation of depressive symptoms was performed using the Hamilton scale. For a possible clinical association between HbA1c levels and depressive symptoms, we performed chi-square tests (
χ
2
)/
t
tests. A multivariate logistic regression model with the backward conditional method was used to identify predictors of depressive symptoms. An ROC curve was plotted to assess the possible role of HbA1c as a diagnostic predictive test of depression symptoms.
Results
A total of 42.8% (
n
= 161) individuals showed clinical depressive symptoms. When comparing individuals with and without depression symptoms, those with depression symptoms showed higher levels of glucose and HbA1c; additionally, gender (
p
= 0.04), age (
p
= 0.006), HbA1c (
p
< 0.01), and complications related to diabetes were predictive factors for clinical depressive symptoms (
p
< 0.01). However, HbA1c showed a low diagnostic accuracy for depressive symptoms, with an area under the ROC curve of 0.59.
Conclusions
Our findings provided evidence of the sex, age, HbA1c levels, and medical complications as predictors of clinical depressive symptoms in individuals with diabetes mellitus. Nevertheless, HbA1c levels are not useful as a diagnostic instrument for depressive symptom severity in these Mexican individuals.</description><identifier>ISSN: 0973-3930</identifier><identifier>EISSN: 1998-3832</identifier><identifier>DOI: 10.1007/s13410-023-01232-1</identifier><language>eng</language><publisher>New Delhi: Springer India</publisher><subject>Comorbidity ; Diabetes ; Diabetes mellitus (non-insulin dependent) ; Family Medicine ; General Practice ; Health Administration ; Medicine ; Medicine & Public Health ; Mental depression ; Original Article ; Population studies</subject><ispartof>International journal of diabetes in developing countries, 2024-09, Vol.44 (3), p.585-591</ispartof><rights>The Author(s), under exclusive licence to Research Society for Study of Diabetes in India 2023. Springer Nature or its licensor (e.g. a society or other partner) holds exclusive rights to this article under a publishing agreement with the author(s) or other rightsholder(s); author self-archiving of the accepted manuscript version of this article is solely governed by the terms of such publishing agreement and applicable law.</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><cites>FETCH-LOGICAL-c270t-6da20695db157899b4e2993fa0c723b2c1f081dd22aba3fb94c0be31f94a5e5a3</cites><orcidid>0000-0001-8170-8171</orcidid></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,777,781,27905,27906</link.rule.ids></links><search><creatorcontrib>Juárez-Rojop, Isela Esther</creatorcontrib><creatorcontrib>Tovilla-Vidal, Gisselle</creatorcontrib><creatorcontrib>López-Narváez, María Lilia</creatorcontrib><creatorcontrib>Tovilla-Zárate, Carlos Alfonso</creatorcontrib><creatorcontrib>Rodríguez-Sánchez, Esther</creatorcontrib><creatorcontrib>González-Castro, Thelma Beatriz</creatorcontrib><creatorcontrib>Fresán, Ana</creatorcontrib><creatorcontrib>Ramírez-González, Dania</creatorcontrib><creatorcontrib>Hernández-Díaz, Yazmín</creatorcontrib><title>Evaluation of HbA1c levels as probable diagnostic of depression symptoms in Mexican individuals with type 2 diabetes mellitus</title><title>International journal of diabetes in developing countries</title><addtitle>Int J Diabetes Dev Ctries</addtitle><description>Background
Depression is present in individuals with type 2 diabetes mellitus.
Objective
We evaluated the sociodemographic, anthropometric, and clinical features of Mexican individuals with clinical depressive symptoms in order to identify predictors for depression symptoms; finally, we evaluated if HbA1c levels could be used as a probable diagnostic of depressive symptoms in individuals with type 2 diabetes mellitus.
Methods
The population studied consisted of 376 Mexicans with diabetes who were interviewed to collect information about comorbidities and habits. The evaluation of depressive symptoms was performed using the Hamilton scale. For a possible clinical association between HbA1c levels and depressive symptoms, we performed chi-square tests (
χ
2
)/
t
tests. A multivariate logistic regression model with the backward conditional method was used to identify predictors of depressive symptoms. An ROC curve was plotted to assess the possible role of HbA1c as a diagnostic predictive test of depression symptoms.
Results
A total of 42.8% (
n
= 161) individuals showed clinical depressive symptoms. When comparing individuals with and without depression symptoms, those with depression symptoms showed higher levels of glucose and HbA1c; additionally, gender (
p
= 0.04), age (
p
= 0.006), HbA1c (
p
< 0.01), and complications related to diabetes were predictive factors for clinical depressive symptoms (
p
< 0.01). However, HbA1c showed a low diagnostic accuracy for depressive symptoms, with an area under the ROC curve of 0.59.
Conclusions
Our findings provided evidence of the sex, age, HbA1c levels, and medical complications as predictors of clinical depressive symptoms in individuals with diabetes mellitus. Nevertheless, HbA1c levels are not useful as a diagnostic instrument for depressive symptom severity in these Mexican individuals.</description><subject>Comorbidity</subject><subject>Diabetes</subject><subject>Diabetes mellitus (non-insulin dependent)</subject><subject>Family Medicine</subject><subject>General Practice</subject><subject>Health Administration</subject><subject>Medicine</subject><subject>Medicine & Public Health</subject><subject>Mental depression</subject><subject>Original Article</subject><subject>Population studies</subject><issn>0973-3930</issn><issn>1998-3832</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2024</creationdate><recordtype>article</recordtype><recordid>eNp9kLFOwzAQhi0EEqXwAkyWmANnX9LUY1UVilTEArNlJ5fiKk1C7BQ68O64FImN6W74vv90P2PXAm4FQH7nBaYCEpCYgJAoE3HCRkKpaYJTlKdsBCrHBBXCObvwfgOQZXKCI_a12Jl6MMG1DW8rvrQzUfCadlR7bjzv-tYaWxMvnVk3rQ-uOGAldT15f5D8ftuFduu5a_gTfbrCNHEt3c6Vg4khHy688bDviMtDiKVAnm-prl0Y_CU7qyJEV79zzF7vFy_zZbJ6fnicz1ZJIXMIyaQ0EiYqK63I8qlSNiWpFFYGilyilYWoYCrKUkpjDVZWpQVYQlGp1GSUGRyzm2Nu_Od9IB_0ph36Jp7UCAqUnAiBkZJHquhb73uqdNe7ren3WoA-1KyPNetYs_6pWYso4VHyEW7W1P9F_2N9Az1ugbw</recordid><startdate>20240901</startdate><enddate>20240901</enddate><creator>Juárez-Rojop, Isela Esther</creator><creator>Tovilla-Vidal, Gisselle</creator><creator>López-Narváez, María Lilia</creator><creator>Tovilla-Zárate, Carlos Alfonso</creator><creator>Rodríguez-Sánchez, Esther</creator><creator>González-Castro, Thelma Beatriz</creator><creator>Fresán, Ana</creator><creator>Ramírez-González, Dania</creator><creator>Hernández-Díaz, Yazmín</creator><general>Springer India</general><general>Springer Nature B.V</general><scope>AAYXX</scope><scope>CITATION</scope><scope>7T5</scope><scope>H94</scope><scope>K9.</scope><scope>NAPCQ</scope><orcidid>https://orcid.org/0000-0001-8170-8171</orcidid></search><sort><creationdate>20240901</creationdate><title>Evaluation of HbA1c levels as probable diagnostic of depression symptoms in Mexican individuals with type 2 diabetes mellitus</title><author>Juárez-Rojop, Isela Esther ; Tovilla-Vidal, Gisselle ; López-Narváez, María Lilia ; Tovilla-Zárate, Carlos Alfonso ; Rodríguez-Sánchez, Esther ; González-Castro, Thelma Beatriz ; Fresán, Ana ; Ramírez-González, Dania ; Hernández-Díaz, Yazmín</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c270t-6da20695db157899b4e2993fa0c723b2c1f081dd22aba3fb94c0be31f94a5e5a3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2024</creationdate><topic>Comorbidity</topic><topic>Diabetes</topic><topic>Diabetes mellitus (non-insulin dependent)</topic><topic>Family Medicine</topic><topic>General Practice</topic><topic>Health Administration</topic><topic>Medicine</topic><topic>Medicine & Public Health</topic><topic>Mental depression</topic><topic>Original Article</topic><topic>Population studies</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Juárez-Rojop, Isela Esther</creatorcontrib><creatorcontrib>Tovilla-Vidal, Gisselle</creatorcontrib><creatorcontrib>López-Narváez, María Lilia</creatorcontrib><creatorcontrib>Tovilla-Zárate, Carlos Alfonso</creatorcontrib><creatorcontrib>Rodríguez-Sánchez, Esther</creatorcontrib><creatorcontrib>González-Castro, Thelma Beatriz</creatorcontrib><creatorcontrib>Fresán, Ana</creatorcontrib><creatorcontrib>Ramírez-González, Dania</creatorcontrib><creatorcontrib>Hernández-Díaz, Yazmín</creatorcontrib><collection>CrossRef</collection><collection>Immunology Abstracts</collection><collection>AIDS and Cancer Research Abstracts</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Nursing & Allied Health Premium</collection><jtitle>International journal of diabetes in developing countries</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Juárez-Rojop, Isela Esther</au><au>Tovilla-Vidal, Gisselle</au><au>López-Narváez, María Lilia</au><au>Tovilla-Zárate, Carlos Alfonso</au><au>Rodríguez-Sánchez, Esther</au><au>González-Castro, Thelma Beatriz</au><au>Fresán, Ana</au><au>Ramírez-González, Dania</au><au>Hernández-Díaz, Yazmín</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Evaluation of HbA1c levels as probable diagnostic of depression symptoms in Mexican individuals with type 2 diabetes mellitus</atitle><jtitle>International journal of diabetes in developing countries</jtitle><stitle>Int J Diabetes Dev Ctries</stitle><date>2024-09-01</date><risdate>2024</risdate><volume>44</volume><issue>3</issue><spage>585</spage><epage>591</epage><pages>585-591</pages><issn>0973-3930</issn><eissn>1998-3832</eissn><abstract>Background
Depression is present in individuals with type 2 diabetes mellitus.
Objective
We evaluated the sociodemographic, anthropometric, and clinical features of Mexican individuals with clinical depressive symptoms in order to identify predictors for depression symptoms; finally, we evaluated if HbA1c levels could be used as a probable diagnostic of depressive symptoms in individuals with type 2 diabetes mellitus.
Methods
The population studied consisted of 376 Mexicans with diabetes who were interviewed to collect information about comorbidities and habits. The evaluation of depressive symptoms was performed using the Hamilton scale. For a possible clinical association between HbA1c levels and depressive symptoms, we performed chi-square tests (
χ
2
)/
t
tests. A multivariate logistic regression model with the backward conditional method was used to identify predictors of depressive symptoms. An ROC curve was plotted to assess the possible role of HbA1c as a diagnostic predictive test of depression symptoms.
Results
A total of 42.8% (
n
= 161) individuals showed clinical depressive symptoms. When comparing individuals with and without depression symptoms, those with depression symptoms showed higher levels of glucose and HbA1c; additionally, gender (
p
= 0.04), age (
p
= 0.006), HbA1c (
p
< 0.01), and complications related to diabetes were predictive factors for clinical depressive symptoms (
p
< 0.01). However, HbA1c showed a low diagnostic accuracy for depressive symptoms, with an area under the ROC curve of 0.59.
Conclusions
Our findings provided evidence of the sex, age, HbA1c levels, and medical complications as predictors of clinical depressive symptoms in individuals with diabetes mellitus. Nevertheless, HbA1c levels are not useful as a diagnostic instrument for depressive symptom severity in these Mexican individuals.</abstract><cop>New Delhi</cop><pub>Springer India</pub><doi>10.1007/s13410-023-01232-1</doi><tpages>7</tpages><orcidid>https://orcid.org/0000-0001-8170-8171</orcidid></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 0973-3930 |
| ispartof | International journal of diabetes in developing countries, 2024-09, Vol.44 (3), p.585-591 |
| issn | 0973-3930 1998-3832 |
| language | eng |
| recordid | cdi_proquest_journals_3090926113 |
| source | Springer Link |
| subjects | Comorbidity Diabetes Diabetes mellitus (non-insulin dependent) Family Medicine General Practice Health Administration Medicine Medicine & Public Health Mental depression Original Article Population studies |
| title | Evaluation of HbA1c levels as probable diagnostic of depression symptoms in Mexican individuals with type 2 diabetes mellitus |
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