The review of oral adsorbents and their properties

Oral adsorbents have attracted increasing attention as a potential therapeutic strategy for the removal of toxic substances from the gastrointestinal tract. This review aims to provide a comprehensive overview of the structural and mechanic properties of oral adsorbents such as activated charcoal, m...

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Bibliographic Details
Published in:Adsorption : journal of the International Adsorption Society 2024-08, Vol.30 (6), p.1505-1527
Main Authors: Berillo, Dmitriy, Ermukhambetova, Asel
Format: Article
Language:English
Subjects:
Activated carbon
Activated clay
Adsorbents
Adsorption
Alginates
Carbohydrates
Carrageenan
Charcoal
Chemistry
Chemistry and Materials Science
Chitosan
Engineering Thermodynamics
Gastrointestinal system
Heat and Mass Transfer
Industrial Chemistry/Chemical Engineering
Ion exchange
Pectin
Review Paper
Surfaces and Interfaces
Thin Films
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Summary:Oral adsorbents have attracted increasing attention as a potential therapeutic strategy for the removal of toxic substances from the gastrointestinal tract. This review aims to provide a comprehensive overview of the structural and mechanic properties of oral adsorbents such as activated charcoal, medical clays, zeolites, silica-based adsorbents, dietary fibers (carbohydrates alginate, chitosan, pectin, carrageenan etc.), and their physicochemical properties. The review also explores the mechanisms of action of oral adsorbents, including physical adsorption, ion exchange, and specific binding interactions. Furthermore, we provide an overview of the factors that influence the adsorption capacity and selectivity of oral adsorbents. The summary of recent advances in the usage of thiolated adsorbents is discussed, which provides valuable insights into the structural and mechanistic properties of oral adsorbents and their potential as a therapeutic option for the removal of toxic substances from the gastrointestinal tract.
ISSN:0929-5607
1572-8757
DOI:10.1007/s10450-024-00515-1