HPV INFECTION IN MALES: ASSOCIATION WITH CANCER AND IMPORTANCE OF VACCINATION

• Published in: Romanian archives of microbiology and immunology 2023-10, Vol.82 (4), p.273-285
• Main Authors: Apetroaei, Miruna-Maria, Ilie, Marina Ionela, Mahler, Beatrice, Ciolan, Gina, Stoichiţă, Alexandru, Popescu, Oana, Preda, Mădălina, Udeanu, Denisa Ioana, Fâcă, Anca, Sorina, Hîncu, Velescu, Bruno Ştefan, Arsene, Andreea Letiţia
• Format: Article
• Language: English
• Subjects: Cell cycle; Cervical cancer; Cervix; Disease transmission; Drug resistance; Fatalities; Genetic engineering; Genomes; Human papillomavirus; Immunization; Infections; Males; Malignancy; Medical screening; Oropharyngeal cancer; Pathogenesis; Pathogens; Penis; Population; Proteins; Sexually transmitted diseases; STD; Stigma; Vaccination; Viruses
• ISSN: 1222-3891; 2601-9418

The human papillomavirus (HPV) can afflict individuals of both genders. Although HPV is often linked to cervical cancer in females, it is also the primary etiology of various other malignancies, such as anal, penile, and oropharyngeal cancer, that can also impact males. It is of the utmost importance for the male population to possess cognizance regarding the hazards linked with HPV and the significance of receiving vaccination. In this article, we review the pathogenesis of HPV in the male population, encompassing its transmission mode and the plausible enduring consequences. Our analysis highlights the incidence of HPV-associated malignancies in the male population, alongside a comprehensive review of the most recent scientific inquiries on the effectiveness of HPV vaccination in the male demographic. The significance of administering HPV vaccination to the male population shall be expounded upon, with emphasis on its capacity to avoid not solely malignancies but also venereal warts and other disorders that are attributable to HPV. By comprehending the potential hazards linked to HPV and the advantages of immunization, males can proactively safeguard their health and impede the transmission of this prevalent sexually transmitted disease.