Antioxidant intake in relation to serum C-reactive protein in mid-life and older African Americans

Objective: African Americans (AAs) experience greater prevalence of cardiovascular disease (CVD) compared to other ethnic/racial groups. Low-grade chronic inflammation (often quantified by serum C-reactive protein CRP) is a well-documented risk factor for CVD. A healthy diet is plentiful in antioxid...

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Bibliographic Details
Published in:Ethnicity & health 2020-11, Vol.25 (8), p.1132-1144
Main Authors: Rancaño, Katherine M., Ralston, Penny A., Lemacks, Jennifer L., Young-Clark, Iris, Ilich, Jasminka Z.
Format: Article
Language:English
Subjects:
African Americans
Antioxidants
Ascorbic acid
Body mass index
Body weight
C-reactive protein
cardiovascular disease
Cardiovascular diseases
Carotenoids
Diet
Dietary intake
Ethnic factors
Ethnic groups
Ethnicity
Fasting
Females
Food intake
Heart diseases
Inflammation
Low protein diet
Males
Mean
Middle age
Minority & ethnic groups
Nutrients
Obesity
Proteins
Racial groups
Risk factors
Risk reduction
Selenium
Serum
Statistical analysis
Vitamin A
Vitamin C
Vitamins
Women
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Summary:Objective: African Americans (AAs) experience greater prevalence of cardiovascular disease (CVD) compared to other ethnic/racial groups. Low-grade chronic inflammation (often quantified by serum C-reactive protein CRP) is a well-documented risk factor for CVD. A healthy diet is plentiful in antioxidant nutrients and is associated with a lower inflammatory status and CVD risk. Our objective was to examine the relationship between dietary intake of antioxidants (carotenoids, vitamins A, C, E, and selenium) and serum CRP concentrations in mid-life and older AAs, while controlling for confounders. Methods: Data were from the baseline phase of a longitudinal church-based intervention study to reduce CVD risk in AAs. Anthropometrics were measured in a standard manner. Fasting serum samples were analyzed with ELISA for CRP. Multiple-pass 24-hour dietary recalls were used to assess intake; self-reported questionnaires were used to collect demographics. Statistical analyses were performed using SPSS Statistics 21 with the level of significance set at p 
ISSN:1355-7858
1465-3419
DOI:10.1080/13557858.2018.1492707