Cyanothioacetamide in Multicomponent Synthesis of 2-Thionicotinonitrile Derivatives

Multicomponent condensation of cyanothioacetamide, carbonyl compounds, enamines and alkylating reagents initiated by the Knoevenagel reaction led to the formation of 2-thionicotinonitriles. The molecular and crystal structure of the prepared products was studied by single crystal X-ray diffraction m...

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Bibliographic Details
Published in:Russian journal of general chemistry 2024, Vol.94 (6), p.1217-1230
Main Authors: Dyachenko, I. V., Dyachenko, V. D., Dorovatovskiy, P. V., Khrustalev, V. N., Nenaidenko, V. G.
Format: Article
Language:English
Subjects:
Alkylation
Carbonyl compounds
Carbonyls
Chemical synthesis
Chemistry
Chemistry and Materials Science
Chemistry/Food Science
Condensates
Crystal structure
Molecular structure
Reagents
Single crystals
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Summary:Multicomponent condensation of cyanothioacetamide, carbonyl compounds, enamines and alkylating reagents initiated by the Knoevenagel reaction led to the formation of 2-thionicotinonitriles. The molecular and crystal structure of the prepared products was studied by single crystal X-ray diffraction method.
ISSN:1070-3632
1608-3350
DOI:10.1134/S107036322406001X