Natural Hydrogels Support Kidney Organoid Generation and Promote In Vitro Angiogenesis (Adv. Mater. 34/2024)

Kidney Organoids The potential benefit of kidney‐specific extracellular matrix (ECM) proteins to favor kidney organoid derivation and vascularization remains to be revealed. In article number 2400306, Elena Garreta, Nuria Montserrat, and co‐workers show that kidney‐derived decellularized ECM from po...

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Published in:Advanced materials (Weinheim) 2024-08, Vol.36 (34), p.n/a
Main Authors: Garreta, Elena, Moya‐Rull, Daniel, Marco, Andrés, Amato, Gaia, Ullate‐Agote, Asier, Tarantino, Carolina, Gallo, Maria, Esporrín‐Ubieto, David, Centeno, Alberto, Vilas‐Zornoza, Amaia, Mestre, Rafael, Kalil, María, Gorroñogoitia, Izar, Zaldua, Ane Miren, Sanchez, Samuel, Izquierdo Reyes, Laura, Fernández‐Santos, María Eugenia, Prosper, Felipe, Montserrat, Nuria
Format: Article
Language:English
Subjects:
assembloids
Biomedical materials
Derivation
extracellular matrix‐derived hydrogels
human pluripotent stem cells
kidney organoids
Kidneys
vascularization
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Summary:Kidney Organoids The potential benefit of kidney‐specific extracellular matrix (ECM) proteins to favor kidney organoid derivation and vascularization remains to be revealed. In article number 2400306, Elena Garreta, Nuria Montserrat, and co‐workers show that kidney‐derived decellularized ECM from porcine and human renal cortex represent a new biomaterial to sustain the derivation of kidney and endothelial assembloids. Image credit: Solidcam Estudio
ISSN:0935-9648
1521-4095
DOI:10.1002/adma.202470272