Crystallization of chiral thiourea derivatives of 1-phenylethylamine: transfer of stable motifs from racemic to homochiral environment

In a series of three chiral thioureas with a 1-phenylethylamine fragment, none of the homochiral samples forms “true chiral” hydrogen-bonded motifs in the crystal, but forms dimers or chains with local symmetry from the interacting fragments, consistent with the racemic crystal pattern.

Saved in:
Bibliographic Details
Published in:Structural chemistry 2024-12, Vol.35 (6), p.1963-1980
Main Authors: Frantsuzova, Lyubov V., Gerasimova, Daria P., Metlushka, Kirill E., Badeeva, Elena K., Nikitina, Kristina A., Zinnatullin, Ruzal G., Ivshin, Kamil A., Kataeva, Olga N., Lodochnikova, Olga A.
Format: Article
Language:English
Subjects:
Chemistry
Chemistry and Materials Science
Computer Applications in Chemistry
Crystallization
Hydrogen bonding
Phenylethylamine
Physical Chemistry
Theoretical and Computational Chemistry
Thiourea derivatives
Citations: Items that this one cites
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:In a series of three chiral thioureas with a 1-phenylethylamine fragment, none of the homochiral samples forms “true chiral” hydrogen-bonded motifs in the crystal, but forms dimers or chains with local symmetry from the interacting fragments, consistent with the racemic crystal pattern.
ISSN:1040-0400
1572-9001
DOI:10.1007/s11224-024-02343-z