A Novel Approach for Tumor‐Released Methylated DNA Detection Using Molecularly Imprinted Polymers

The convergence of tumor epigenetics and molecularly imprinted polymers (MIPs) holds promise in early cancer diagnostics. To the best of knowledge, none of the studies has achieved DNA methylation detection yet using MIPs and the proposed research will pioneer the application of MIPs for detecting D...

Full description

Saved in:
Bibliographic Details
Published in:Advanced functional materials 2024-11, Vol.34 (45), p.n/a
Main Authors: Khawar, Muhammad Babar, Afzal, Ali, Ali, Muhammad Mujahid, Sun, Haibo
Format: Article
Language:English
Subjects:
cancer detection
DNA methylation
epigenetics
Imprinted polymers
molecularly imprinted polymers
tumor
Tumors
Citations: Items that this one cites
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:The convergence of tumor epigenetics and molecularly imprinted polymers (MIPs) holds promise in early cancer diagnostics. To the best of knowledge, none of the studies has achieved DNA methylation detection yet using MIPs and the proposed research will pioneer the application of MIPs for detecting DNA methylation, introducing a novel approach to enhance early diagnostic precision. DNA methylation shows potential as a biomarkers for different cancer types. However, current detection methods have limitations, leading to the exploration of molecularly imprinted polymers (MIPs) as a solution offering enhanced specificity and sensitivity. In this perspective, the noninvasive early detection of tumor‐released methylated DNA using MIPs for the first time is advocated.
ISSN:1616-301X
1616-3028
DOI:10.1002/adfm.202405786