A Novel Approach for Tumor‐Released Methylated DNA Detection Using Molecularly Imprinted Polymers

The convergence of tumor epigenetics and molecularly imprinted polymers (MIPs) holds promise in early cancer diagnostics. To the best of knowledge, none of the studies has achieved DNA methylation detection yet using MIPs and the proposed research will pioneer the application of MIPs for detecting D...

Full description

Saved in:
Bibliographic Details
Published in:Advanced functional materials 2024-11, Vol.34 (45), p.n/a
Main Authors: Khawar, Muhammad Babar, Afzal, Ali, Ali, Muhammad Mujahid, Sun, Haibo
Format: Article
Language:English
Subjects:
cancer detection
DNA methylation
epigenetics
Imprinted polymers
molecularly imprinted polymers
tumor
Tumors
Citations: Items that this one cites
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
cited_by
cites cdi_FETCH-LOGICAL-c2726-9f2811d57f5153384114531711e3dc5493304fdd7de63e6d2b3c723c7e59b4653
container_end_page n/a
container_issue 45
container_start_page
container_title Advanced functional materials
container_volume 34
creator Khawar, Muhammad Babar
Afzal, Ali
Ali, Muhammad Mujahid
Sun, Haibo
description The convergence of tumor epigenetics and molecularly imprinted polymers (MIPs) holds promise in early cancer diagnostics. To the best of knowledge, none of the studies has achieved DNA methylation detection yet using MIPs and the proposed research will pioneer the application of MIPs for detecting DNA methylation, introducing a novel approach to enhance early diagnostic precision. DNA methylation shows potential as a biomarkers for different cancer types. However, current detection methods have limitations, leading to the exploration of molecularly imprinted polymers (MIPs) as a solution offering enhanced specificity and sensitivity. In this perspective, the noninvasive early detection of tumor‐released methylated DNA using MIPs for the first time is advocated.
doi_str_mv 10.1002/adfm.202405786
format article
fullrecord <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_journals_3123690036</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>3123690036</sourcerecordid><originalsourceid>FETCH-LOGICAL-c2726-9f2811d57f5153384114531711e3dc5493304fdd7de63e6d2b3c723c7e59b4653</originalsourceid><addsrcrecordid>eNqFkL1OwzAUhSMEEqWwMltibvG1YycZo5ZCpbYg1EpsVprc0FROXOwElI1H4Bl5ElIVlZHh6p7hO_fneN410CFQym6TLC-HjDKfiiCUJ14PJMgBpyw8PWp4OfcunNtSCkHA_Z6XxmRh3lGTeLezJkk3JDeWLJvS2O_Pr2fUmDjMyBzrTauTupPjRUzGWGNaF6YiK1dUr2RuNKaNTqxuybTc2aLak09GtyVad-md5Yl2ePXb-95qcrccPQxmj_fTUTwbpCxgchDlLATIRJALEJyHPoAvOAQAyLNU-BHn1M-zLMhQcpQZW_M0YF2hiNa-FLzv3Rzmdp-8NehqtTWNrbqVigPjMqKUy44aHqjUGucs5qq7t0xsq4CqfZBqH6Q6BtkZooPho9DY_kOreDyZ_3l_AHl4d1A</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>3123690036</pqid></control><display><type>article</type><title>A Novel Approach for Tumor‐Released Methylated DNA Detection Using Molecularly Imprinted Polymers</title><source>Wiley-Blackwell Read &amp; Publish Collection</source><creator>Khawar, Muhammad Babar ; Afzal, Ali ; Ali, Muhammad Mujahid ; Sun, Haibo</creator><creatorcontrib>Khawar, Muhammad Babar ; Afzal, Ali ; Ali, Muhammad Mujahid ; Sun, Haibo</creatorcontrib><description>The convergence of tumor epigenetics and molecularly imprinted polymers (MIPs) holds promise in early cancer diagnostics. To the best of knowledge, none of the studies has achieved DNA methylation detection yet using MIPs and the proposed research will pioneer the application of MIPs for detecting DNA methylation, introducing a novel approach to enhance early diagnostic precision. DNA methylation shows potential as a biomarkers for different cancer types. However, current detection methods have limitations, leading to the exploration of molecularly imprinted polymers (MIPs) as a solution offering enhanced specificity and sensitivity. In this perspective, the noninvasive early detection of tumor‐released methylated DNA using MIPs for the first time is advocated.</description><identifier>ISSN: 1616-301X</identifier><identifier>EISSN: 1616-3028</identifier><identifier>DOI: 10.1002/adfm.202405786</identifier><language>eng</language><publisher>Hoboken: Wiley Subscription Services, Inc</publisher><subject>cancer detection ; DNA methylation ; epigenetics ; Imprinted polymers ; molecularly imprinted polymers ; tumor ; Tumors</subject><ispartof>Advanced functional materials, 2024-11, Vol.34 (45), p.n/a</ispartof><rights>2024 Wiley‐VCH GmbH</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><cites>FETCH-LOGICAL-c2726-9f2811d57f5153384114531711e3dc5493304fdd7de63e6d2b3c723c7e59b4653</cites><orcidid>0000-0002-1812-0591 ; 0000-0003-3679-1257</orcidid></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,776,780,27903,27904</link.rule.ids></links><search><creatorcontrib>Khawar, Muhammad Babar</creatorcontrib><creatorcontrib>Afzal, Ali</creatorcontrib><creatorcontrib>Ali, Muhammad Mujahid</creatorcontrib><creatorcontrib>Sun, Haibo</creatorcontrib><title>A Novel Approach for Tumor‐Released Methylated DNA Detection Using Molecularly Imprinted Polymers</title><title>Advanced functional materials</title><description>The convergence of tumor epigenetics and molecularly imprinted polymers (MIPs) holds promise in early cancer diagnostics. To the best of knowledge, none of the studies has achieved DNA methylation detection yet using MIPs and the proposed research will pioneer the application of MIPs for detecting DNA methylation, introducing a novel approach to enhance early diagnostic precision. DNA methylation shows potential as a biomarkers for different cancer types. However, current detection methods have limitations, leading to the exploration of molecularly imprinted polymers (MIPs) as a solution offering enhanced specificity and sensitivity. In this perspective, the noninvasive early detection of tumor‐released methylated DNA using MIPs for the first time is advocated.</description><subject>cancer detection</subject><subject>DNA methylation</subject><subject>epigenetics</subject><subject>Imprinted polymers</subject><subject>molecularly imprinted polymers</subject><subject>tumor</subject><subject>Tumors</subject><issn>1616-301X</issn><issn>1616-3028</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2024</creationdate><recordtype>article</recordtype><recordid>eNqFkL1OwzAUhSMEEqWwMltibvG1YycZo5ZCpbYg1EpsVprc0FROXOwElI1H4Bl5ElIVlZHh6p7hO_fneN410CFQym6TLC-HjDKfiiCUJ14PJMgBpyw8PWp4OfcunNtSCkHA_Z6XxmRh3lGTeLezJkk3JDeWLJvS2O_Pr2fUmDjMyBzrTauTupPjRUzGWGNaF6YiK1dUr2RuNKaNTqxuybTc2aLak09GtyVad-md5Yl2ePXb-95qcrccPQxmj_fTUTwbpCxgchDlLATIRJALEJyHPoAvOAQAyLNU-BHn1M-zLMhQcpQZW_M0YF2hiNa-FLzv3Rzmdp-8NehqtTWNrbqVigPjMqKUy44aHqjUGucs5qq7t0xsq4CqfZBqH6Q6BtkZooPho9DY_kOreDyZ_3l_AHl4d1A</recordid><startdate>20241101</startdate><enddate>20241101</enddate><creator>Khawar, Muhammad Babar</creator><creator>Afzal, Ali</creator><creator>Ali, Muhammad Mujahid</creator><creator>Sun, Haibo</creator><general>Wiley Subscription Services, Inc</general><scope>AAYXX</scope><scope>CITATION</scope><scope>7SP</scope><scope>7SR</scope><scope>7U5</scope><scope>8BQ</scope><scope>8FD</scope><scope>JG9</scope><scope>L7M</scope><orcidid>https://orcid.org/0000-0002-1812-0591</orcidid><orcidid>https://orcid.org/0000-0003-3679-1257</orcidid></search><sort><creationdate>20241101</creationdate><title>A Novel Approach for Tumor‐Released Methylated DNA Detection Using Molecularly Imprinted Polymers</title><author>Khawar, Muhammad Babar ; Afzal, Ali ; Ali, Muhammad Mujahid ; Sun, Haibo</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c2726-9f2811d57f5153384114531711e3dc5493304fdd7de63e6d2b3c723c7e59b4653</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2024</creationdate><topic>cancer detection</topic><topic>DNA methylation</topic><topic>epigenetics</topic><topic>Imprinted polymers</topic><topic>molecularly imprinted polymers</topic><topic>tumor</topic><topic>Tumors</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Khawar, Muhammad Babar</creatorcontrib><creatorcontrib>Afzal, Ali</creatorcontrib><creatorcontrib>Ali, Muhammad Mujahid</creatorcontrib><creatorcontrib>Sun, Haibo</creatorcontrib><collection>CrossRef</collection><collection>Electronics &amp; Communications Abstracts</collection><collection>Engineered Materials Abstracts</collection><collection>Solid State and Superconductivity Abstracts</collection><collection>METADEX</collection><collection>Technology Research Database</collection><collection>Materials Research Database</collection><collection>Advanced Technologies Database with Aerospace</collection><jtitle>Advanced functional materials</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Khawar, Muhammad Babar</au><au>Afzal, Ali</au><au>Ali, Muhammad Mujahid</au><au>Sun, Haibo</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>A Novel Approach for Tumor‐Released Methylated DNA Detection Using Molecularly Imprinted Polymers</atitle><jtitle>Advanced functional materials</jtitle><date>2024-11-01</date><risdate>2024</risdate><volume>34</volume><issue>45</issue><epage>n/a</epage><issn>1616-301X</issn><eissn>1616-3028</eissn><abstract>The convergence of tumor epigenetics and molecularly imprinted polymers (MIPs) holds promise in early cancer diagnostics. To the best of knowledge, none of the studies has achieved DNA methylation detection yet using MIPs and the proposed research will pioneer the application of MIPs for detecting DNA methylation, introducing a novel approach to enhance early diagnostic precision. DNA methylation shows potential as a biomarkers for different cancer types. However, current detection methods have limitations, leading to the exploration of molecularly imprinted polymers (MIPs) as a solution offering enhanced specificity and sensitivity. In this perspective, the noninvasive early detection of tumor‐released methylated DNA using MIPs for the first time is advocated.</abstract><cop>Hoboken</cop><pub>Wiley Subscription Services, Inc</pub><doi>10.1002/adfm.202405786</doi><tpages>5</tpages><orcidid>https://orcid.org/0000-0002-1812-0591</orcidid><orcidid>https://orcid.org/0000-0003-3679-1257</orcidid></addata></record>
fulltext fulltext
identifier ISSN: 1616-301X
ispartof Advanced functional materials, 2024-11, Vol.34 (45), p.n/a
issn 1616-301X
1616-3028
language eng
recordid cdi_proquest_journals_3123690036
source Wiley-Blackwell Read & Publish Collection
subjects cancer detection
DNA methylation
epigenetics
Imprinted polymers
molecularly imprinted polymers
tumor
Tumors
title A Novel Approach for Tumor‐Released Methylated DNA Detection Using Molecularly Imprinted Polymers
url http://sfxeu10.hosted.exlibrisgroup.com/loughborough?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-27T10%3A44%3A43IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_cross&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=A%20Novel%20Approach%20for%20Tumor%E2%80%90Released%20Methylated%20DNA%20Detection%20Using%20Molecularly%20Imprinted%20Polymers&rft.jtitle=Advanced%20functional%20materials&rft.au=Khawar,%20Muhammad%20Babar&rft.date=2024-11-01&rft.volume=34&rft.issue=45&rft.epage=n/a&rft.issn=1616-301X&rft.eissn=1616-3028&rft_id=info:doi/10.1002/adfm.202405786&rft_dat=%3Cproquest_cross%3E3123690036%3C/proquest_cross%3E%3Cgrp_id%3Ecdi_FETCH-LOGICAL-c2726-9f2811d57f5153384114531711e3dc5493304fdd7de63e6d2b3c723c7e59b4653%3C/grp_id%3E%3Coa%3E%3C/oa%3E%3Curl%3E%3C/url%3E&rft_id=info:oai/&rft_pqid=3123690036&rft_id=info:pmid/&rfr_iscdi=true