Synthesis of Betulin and Allobetulin Derivatives Containing Heterylthioacetoxyl Groups

Previously unknown betulin and allobetulin derivatives, which are of interest as potential biologically active substances, were synthesized by replacing chlorine in 3,28-bis(chloroacetoxy)betulin and 3-chloroacetoxyallobetulin with pharmacophoric cycloheteryl sulfide groups.

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Bibliographic Details
Published in:Russian journal of general chemistry 2024-10, Vol.94 (10), p.2623-2631
Main Authors: Trishin, Yu. G., Vakhrusheva, E. D., Anisimova, N. A., Derkacheva, O. Y., Baichurin, R. I., Rizvanov, I. Kh
Format: Article
Language:English
Subjects:
Chemistry
Chemistry and Materials Science
Chemistry/Food Science
Chlorine
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Description
Summary:Previously unknown betulin and allobetulin derivatives, which are of interest as potential biologically active substances, were synthesized by replacing chlorine in 3,28-bis(chloroacetoxy)betulin and 3-chloroacetoxyallobetulin with pharmacophoric cycloheteryl sulfide groups.
ISSN:1070-3632
1608-3350
DOI:10.1134/S1070363224100074