Aphrodisiac Potential of the Ficus religiosa Bark Extract in Male Wistar Rats

• Published in: Research journal of pharmacy and technology 2024-09, Vol.17 (9), p.4363-4369
• Main Authors: Tigote, Asmita A, Shinde, Aishwarya S, Naikwade, Nilofer S, Shikalgar, Tabassum S, Ladda, Padma L
• Format: Article
• Language: English
• Subjects: Animals; Behavior; Cholesterol; Enzymes; Ethanol; Experiments; Females; Fertility; Flavonoids; Herbal medicine; Infertility; Ligands; Medical research; Phytochemicals; Reproductive health; Rodents; Sexual disorders; Sperm; Testosterone
• ISSN: 0974-3618; 0974-360X; 0974-306X
• DOI: 10.52711/0974-360X.2024.00674

Medicinal properties of Ficus religiosa bark. are well documented. Its reproductive system related activities are mentioned in Ayurveda system of medicine. However, studies evaluating its Aphrodisiac properties and the underlying mechanisms are lacking. We investigate Aphrodisiac activity of Ethanolic extract of Ficus religiosa bark by using animal models such as physical methods mount and intromission frequencies and latencies, orientation behaviour tests, histological studies, sperm count, total cholesterol level and total serum testosterone level, were also estimated. The phytoconstituents were extracted using Soxhlet apparatus. The male albino rats were orally administered with the test extract and standard drug sildenafil citrate for 21 days. Aphrodisiac activity was assessed using physical methods mount and intromission frequencies and latencies, orientation behaviour tests on 1, 7, 14 and 21. On the 22th day, The effect of the extract on body weight, reproductive and increase in perm count, total cholesterol and testosterone level were determined. significantly increased the MI, IF and with reduction in Mounting Latency, Intromission. Thus, our study concludes that the ethanolic extract of Ficus religiosa bark shows Aphrodisiac activity.