Adjuvant Potential of Diadema Setosum Spine’s Toxin On Macrophages

Sea urchins are marine species originating from the Indo-Pacific and Red Sea regions, having a natural immune system, acting as biocorrosives in coral ecosystems, rich in polyunsaturated fatty acids (PUFAs) and bioactive components, and generally feeding on rock bottoms and coral reefs as herbivores...

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Bibliographic Details
Published in:Thalassas : revista de ciencias del mar 2025-03, Vol.41 (1), p.23
Main Authors: Türkben, Havva, Canatar, Ceren, Yetkin, Derya, Ayas, Deniz, Ayaz, Furkan
Format: Article
Language:English
Subjects:
Adjuvants
Biodiversity
Biological effects
Cell division
Coastal Sciences
Consortia
Coral reefs
Cytokines
Earth and Environmental Science
Earth Sciences
Echinoidea
Economic importance
Fatty acids
Fish & Wildlife Biology & Management
Food
Freshwater & Marine Ecology
Genomics
Herbivores
Immune system
Macrophages
Marine & Freshwater Sciences
Marine ecosystems
Marine invertebrates
Nervous system
Oceanography
Polyunsaturated fatty acids
Sea urchins
Spine
Toxins
Vaccines
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Summary:Sea urchins are marine species originating from the Indo-Pacific and Red Sea regions, having a natural immune system, acting as biocorrosives in coral ecosystems, rich in polyunsaturated fatty acids (PUFAs) and bioactive components, and generally feeding on rock bottoms and coral reefs as herbivores. Studies are being carried out on Sea urchins as they have the potential to gain economic importance by evaluating their use as biological agents. This study focused on the effects and adjuvant potential of the spine toxin of Diadema setosum, a sea urchin species, on mammalian macrophage cells. Our results suggest that the extracts from this species have adjuvant potential to be utilized in vaccine formulations.
ISSN:0212-5919
2366-1674
DOI:10.1007/s41208-024-00780-5