Treatment of Grade II Furcation Defect with Xenograft in Combination with Hyaluronic Acid

Management of furcation involvement presents one of the greatest challenges in periodontal therapy. Furcation-involved molar teeth respond less favorably to conventional periodontal therapy. Advances in understanding inflammatory mechanisms and wound-healing processes associated with periodontal dis...

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Bibliographic Details
Published in:Journal of the International Clinical Dental Research Organization 2023-01, Vol.15 (1), p.58-60
Main Authors: Joshi, Salil, Agarwal, Mrinalini, Kaushik, Mayur, Sharma, Apoorva
Format: Article
Language:English
Subjects:
Bone grafts
Case reports
Extracellular matrix
Hyaluronic acid
Periodontal diseases
Periodontitis
Periodontium
Regeneration
Wound healing
Xenografts
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Summary:Management of furcation involvement presents one of the greatest challenges in periodontal therapy. Furcation-involved molar teeth respond less favorably to conventional periodontal therapy. Advances in understanding inflammatory mechanisms and wound-healing processes associated with periodontal diseases have led researchers to study the potential of numerous extracellular matrix (ECM) components as promoters of periodontal healing and regeneration. Hyaluronic acid (HA) is one such ECM component, which plays a vital role in the functioning of extracellular matrices of the periodontium. The aim of the present case report is to evaluate the effect of HA with xenograft in treatment of Grade II furcation defect. A single patient of chronic periodontitis was treated with open flap debridement followed by placement of xenograft (ColoCast ® ) along with 1% HA. Clinical parameters such as Pocket Probing Depth (PPD), Horizontal Furcation Depth (HFD), and bleeding on probing were recorded at baseline and 6 months. There was a marked reduction in clinical parameters along with the evidence of radiographic bone fill of the defect at 6 months. Present case report suggests that application of HA in combination with bone graft leads to improvement in clinical parameters and radiographic bone fill.
ISSN:2231-0754
2231-5357
DOI:10.4103/jicdro.jicdro_63_22