Comparative shelf-life study of Raw Guggulu (Commiphora wightii oleo-gum resin) and Shodhita Guggulu (cow urine processed C. wightii oleo-gum resin)

BACKGROUND: Shelf-life is an important aspect of raw as well as finished drugs. Recently, shelf-life parameters have been included in the Ayurvedic Pharmacopeia of India. The objective of this article is to evaluate and compare the long-term shelf-life study of Raw Guggulu (RG) (C. wightii oleo-gum...

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Published in:Journal of Drug Research in Ayurvedic Sciences 2022-01, Vol.7 (1), p.47-54
Main Authors: Charde, Vaibhav, Jagtap, Chandrashekar, Kumar, Vijay, Kushwaha, Vikram, Grewal, Jyotika, Mishra, Sujeet, Shakya, Santosh, Soni, Hemant, Singh, Gagandeep, Babu, Gajji, Singh, Arjun, Singh, Ravindra, Khanduri, Shruti, Sharma, Bhagwan, Srikanth, Narayanam
Format: Article
Language:English
Subjects:
Ayurvedic medicine
Medical research
Pharmacology
Resins
Urine
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Summary:BACKGROUND: Shelf-life is an important aspect of raw as well as finished drugs. Recently, shelf-life parameters have been included in the Ayurvedic Pharmacopeia of India. The objective of this article is to evaluate and compare the long-term shelf-life study of Raw Guggulu (RG) (C. wightii oleo-gum resin) and Shodhita Guggulu (SG) (cow urine processed C. wightii oleo-gum resin). MATERIALS AND METHODS: A stability chamber with environmental conditions 30°C ± 2°C/60% ± 5% RH was used for long-term shelf-life study of RG and SG. Physico-chemical parameters such as loss on drying, pH, total ash, acid-insoluble ash, water extractive value, and alcohol extractive value were tested at regular frequency (0th, 3rd, 6th, 9th, and 12th month). RESULTS: Significant changes have been observed w.r.t. analysis of physico-chemical parameters. Physico-chemical parameters revealed that the shelf-life of RG ranged from 42 to 66 months and shelf-life of SG ranged from 39 to 62 months. CONCLUSION: The average shelf-life of RG and SG was found out to be 55.16 and 48.16 months, respectively. These studies may help to understand the shelf-life of various ayurvedic formulations of RG and SG.
ISSN:2279-0357
2581-8295
DOI:10.4103/jdras.JDRAS_14_22