Synthesis and Study of Luminescent, Anti-Mao, and Antioxidant Properties of (2E)-3-Aryl-1-(4-alkoxyphenyl)prop-2-ene-1-ones and Their Pyrazoline Derivatives

By condensation of 1-(4-alkoxyphenyl)ethanones with aromatic aldehydes in the presence of sodium hydroxide in an aqueous-ethanol solution, (2 E )-3-aryl-1-(4-alkoxyphenyl)prop-2-ene-1-ones were obtained. Cyclization of these latter with phenylhydrazine in an acidic medium leads to the corresponding...

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Bibliographic Details
Published in:Russian journal of general chemistry 2024, Vol.94 (11), p.2847-2858
Main Authors: Hakobyan, N. Z., Isakhanyan, A. U., Grigoryan, G. S., Mkhitaryan, R. P., Sargsyan, H. R., Grigoryan, A. S., Pahutyan, N. H., Pogosyan, A. E., Аrajyan, G. М., Gasparyan, H. V., Muradyan, R. Y., Panosyan, Н. A., Israelyan, S. G., Harutyunyan, A. A.
Format: Article
Language:English
Subjects:
Acidic oxides
Aldehydes
Antioxidants
Aromatic compounds
Chemistry
Chemistry and Materials Science
Chemistry/Food Science
Ethanol
Sodium hydroxide
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Summary:By condensation of 1-(4-alkoxyphenyl)ethanones with aromatic aldehydes in the presence of sodium hydroxide in an aqueous-ethanol solution, (2 E )-3-aryl-1-(4-alkoxyphenyl)prop-2-ene-1-ones were obtained. Cyclization of these latter with phenylhydrazine in an acidic medium leads to the corresponding 5-aryl-3-(4-alkoxyphenyl)-1-phenyl-4,5-dihydro-1 H -pyrazoles. The luminescent, antimonoamine oxidase, and antioxidant properties of the compounds obtained were studied.
ISSN:1070-3632
1608-3350
DOI:10.1134/S1070363224110057